Any long haulers develop new onset of depression? What helps?

Posted by MelissaDawn @mdawn, Jul 25, 2022

Its been almost 2 years since my husband had covid. He us a long hauler with many complications from the infection. He sees many doctors and has had numerous testing done. He is now dealing with intense depression with mood swings. When will this end? How can I help him?

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Profile picture for kprcyan42 @kprcyan42

I have never been a smoker. No experience with Nicotine.

I had the first COVID in very early March 2020. I asked my PCP for a test to confirm but was told that since I could breathe no test could be spared for me. I was also told NOT to go to the ER since they were over-whelmed anyway and could not treat a person who was breathing properly. I believe March 2, 2020 is when my Stroke and brain damage occurred. I had a very low BP event, passed out in my easy chair. When I woke my fdirst home BP reult was 74/42.

I have now been diagnosed with a "Lacunar infarction of my right Putamen and right Basal Ganglia". The stroke has resulted in a permanent physical depression and cognitive imparemnet for which there is currently no treatment and obviously no cure with current medicine. I was hoping that my memory would improve over the last five years but I was made aware this year that it's getting worse. I was fired from my job as a Linux Admin/Engineer in August 2025 because I can no longer perform my duties due to my cognitive impairment. I have forty years experience in IT support. But I can no longer solve even simple IT issues. This compelled me to find out my true state of decline by seeking a brain scan to assess my cognitive state. I got the MRI in August 2025 but it was too late. My contract position had already been eliminated. I filed for SSA retirement and SSA disability. My disability claim has been unofficially approved but I won't get the letter until February 2026. Almost six years since my first COVID infection. COVID, even from the first strain, continues to destroy the lives of its victims and cause death.

I believe with each new infection, COVID and other flu infections, attacks my brain anew and inflicts further damage. Although I wore my masks as directed and got all the booster shots, I was still infected with newer COVID strains at least once more after 2020. I will try to preserve my brain, such as it is, and donate it to science for study of the effects of COVID. But I need treatment. I have been hoping that some kind of stem-cell therapy for new neuron growth would be developed to help patients like me recover damaged brain tissue in the basal ganglia and putamen or other brain tissue. There is an on-going study along these lines but I don't know how far along the path to real treatment the study is. It's not happening quickly enough for me.

I have had to retype this post four times and it's taken me hours to get it to this quality of statement. Correcting spelling errors, and trying to clearly state my experience as completely as I can. I hope it's readable and cleanly understandable. I have a tendency to invent new words now since I have trouble remembering words that might make more sense. It's 4:30 AM EST and I cannot get to sleep. I wish COVID had killed me in 2020. It would have been kinder.

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@kprcyan42

I am so sorry this has happened to you.

I would scour PubMed for experts on this. Usually, you can reach out to the specific doctors doing the research. They may be able to give you guidance or remote consultation, or if you're able to travel to them, you may be able to get help.

Again, I can only imagine how scary and frustrating this is.

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@suefish here
Tremendous depression. Talking here does a great deal of good. I seem to be developing some new problems and to be feel more strongly of the old. Very depressing but having this group helps. Tuesday 2 pm

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My 72 year old mother is dealing with bad depression now too after contracting covid in 2021. She does not seem to be getting any better with that or any of the other problems she is still dealing with. I don't know what to do. She won't go to doctors anymore and it seems like she is giving up on life. It's really sad to sit at home all day as her full time caregiver and watch her deteriate slowly right in front of my eyes. I wish there was something they could develop to help that specific part of their brain. God Bless my Mom and all the long hauler's.

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Profile picture for kprcyan42 @kprcyan42

I have never been a smoker. No experience with Nicotine.

I had the first COVID in very early March 2020. I asked my PCP for a test to confirm but was told that since I could breathe no test could be spared for me. I was also told NOT to go to the ER since they were over-whelmed anyway and could not treat a person who was breathing properly. I believe March 2, 2020 is when my Stroke and brain damage occurred. I had a very low BP event, passed out in my easy chair. When I woke my fdirst home BP reult was 74/42.

I have now been diagnosed with a "Lacunar infarction of my right Putamen and right Basal Ganglia". The stroke has resulted in a permanent physical depression and cognitive imparemnet for which there is currently no treatment and obviously no cure with current medicine. I was hoping that my memory would improve over the last five years but I was made aware this year that it's getting worse. I was fired from my job as a Linux Admin/Engineer in August 2025 because I can no longer perform my duties due to my cognitive impairment. I have forty years experience in IT support. But I can no longer solve even simple IT issues. This compelled me to find out my true state of decline by seeking a brain scan to assess my cognitive state. I got the MRI in August 2025 but it was too late. My contract position had already been eliminated. I filed for SSA retirement and SSA disability. My disability claim has been unofficially approved but I won't get the letter until February 2026. Almost six years since my first COVID infection. COVID, even from the first strain, continues to destroy the lives of its victims and cause death.

I believe with each new infection, COVID and other flu infections, attacks my brain anew and inflicts further damage. Although I wore my masks as directed and got all the booster shots, I was still infected with newer COVID strains at least once more after 2020. I will try to preserve my brain, such as it is, and donate it to science for study of the effects of COVID. But I need treatment. I have been hoping that some kind of stem-cell therapy for new neuron growth would be developed to help patients like me recover damaged brain tissue in the basal ganglia and putamen or other brain tissue. There is an on-going study along these lines but I don't know how far along the path to real treatment the study is. It's not happening quickly enough for me.

I have had to retype this post four times and it's taken me hours to get it to this quality of statement. Correcting spelling errors, and trying to clearly state my experience as completely as I can. I hope it's readable and cleanly understandable. I have a tendency to invent new words now since I have trouble remembering words that might make more sense. It's 4:30 AM EST and I cannot get to sleep. I wish COVID had killed me in 2020. It would have been kinder.

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@kprcyan42, I am so sorry for what you’ve endured, and please know you’re not alone. I’ve had a TIA, but don’t know when I had it. I suspect it occurred the first time I had Covid, and I didn’t see or feel any symptoms because I slept for almost 5 days. Because all my Long Covid symptoms have improved except brain fog, memory, loss, anxiety, and heat intolerance. I suspect the TIA or Covid damaged brain cells and as a result, I’ll never see the brain fog and memory loss improve. I was even tested in 2022 for dementia, and didn’t have it or any of the other brain disorders I was tested for. All the doctor could say was, “It must be Long Covid.” Fortunately, I retired before I had Covid, but was a very active retiree. I volunteered in a nonprofit office, which I had to give up when I couldn’t recall what I was supposed to do or how to do something as simple as filing invoices. I sang in the choir, but had to drop out because reading music became so difficult. I have a degree in music, and never expected that. Having a conversation is still difficult because I know what I want to say, but can’t find the words to say it. All this increases my anxiety, sometimes to the point of a panic attack. And due to geat intolerance, I can’t even play outside with my grandchildren if it’s over 80 degrees, which happens a lot here in Alabama. Like you, I’ve also had to proof and correct this message several times, because brain fog keeps me from writing anything correctly the first time. My issues aren’t as severe as yours, but I understand why your depression would be so bad. I can’t get off my antidepressants - I’ve tried. But at least they give me somewhat of a lift. I pray you find help and improvement soon!

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Update. Dec 2025 will be 6 years since my husband became sick with covid 19. He still has severe long covid. He is now disabled. Physical and Mental health is very bad. When will this end for him and others. There's nowhere to turn.

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I have a history of depression but oddly enough what I notice since having long Covid is an increase in anxiety. Has anyone noticed this?

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Profile picture for MelissaDawn @mdawn

Thank you for doing that Collen. It's so hard watching someone you love change so drastically.

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@mdawn Yes it is.Keep being hopeful.Things change.EVERYTHING changes.God Bless...

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Profile picture for shario @shario

I have a history of depression but oddly enough what I notice since having long Covid is an increase in anxiety. Has anyone noticed this?

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@shario Yes.For a while I was taking Lorazapam.About 2-3 weeks on and off.This isn't the best way to go if you have any sort of 'addictive' behaviors.I do.So seeing and feeling the difference was important to be able to judge how I felt.I stopped after that period.It did help me be much calmer mentally.I knew I couldn't keep doing it though.So I stopped.LOW LOW dose.The lowest I could get.

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Profile picture for suefish @suefish

@suefish here
Tremendous depression. Talking here does a great deal of good. I seem to be developing some new problems and to be feel more strongly of the old. Very depressing but having this group helps. Tuesday 2 pm

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@suefish Ditto on all counts.

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I had depression and anxiety prior to COVID. After COVID the depression got worse. I developed Chronic Fatigue about 6 months after. Now I’m a slug. I have exhaustion morning to night. I’m always planning ahead about going out shopping or whatever and 95% of the time I never go anywhere. I go for hair and doctors appointments. I’ve given up on getting my old life back. I do random chores around the house. Occasionally I make supper, clean a bathroom or get laundry in the washer. When CFS is in full effect I sit in my chair constantly falling asleep. Christmas is coming and I’m try to make three quilts and a crocheted afghan. One quilt top is complete. The afghan is half done. Sewing on the second quilt and need a plan for the third. No pressure right? But I’m determined. It’s hard to muster this much energy! Decision making is hard too. My daughter helps me. I have an occasional housekeeper. Life is very hard. My husband does so much. I do so little. Exhaustion rules every day. My doctor is considering ADHD for motivation to get me moving! I’d like to try it

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