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Anyone taking Hydroxyurea for ET and Prolia for Osteoporosis?
Blood Cancers & Disorders | Last Active: Nov 1, 2025 | Replies (8)Comment receiving replies
I tried fosomax for 2 weeks back in 2010 and had the worst joint issues and swelling so went off. I’ve never felt so achy. About 10 years later PCP said I had to do something so we tried another variation and same issues. Finally after seeing an rheumatologist for and the reaction to the two osteoporosis drugs the insurance approved Prolia. I have been taking it for about 4 years twice a year and no issues. However I can’t go back and take the ones that build bones like Forteo which my doctor wishes we had tried first. I also started taking hydroxurea last February because platelets were over a million. They are now down into the 400’s. I am 73 ride horse, bike and lift weights. Everyone reacts differently to these drugs so good luck.
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I have bern in both drugs. I am on prolia for osteopenia for 3 yrs now no problems. I was more scared of getting fractures. I fell and fractured L1 and L5 vertebrae. The worst pain I ever went through in my life. I also took hydroxy for a year. Started with 1000mg and then 500mg once a day for low platelets. I had MDS then. No problem except my red cells went down. I now have progressed to AML. I am doing the 7+3 days chemo infusions and take a chemo pill with it. I am finishing my second cycle Tuesday. I did a bone marrow biopsy that I am still waiting on results and I will do a blood test on Monday to see if it put me in remission. The treatment was not bad at all. It’s just all the medication you have to remember to take with it. I did accelerated chemo 18 yrs ago for breast cancer and 25 radiation treatments and 3 boosters. They think this might be why I have Leukemia. I trust my doctors especially my oncologist. I went 9 years with MDS before I had to start treatments. Hang in there. Prolia is fine and it prevents fractures. I had to learn not to read google. It scares you to death. Good luck.