I am 73 and was on Agralyn for about 17 years. I am type 2 diabetic. I had no side affects with Agralyn. Wish I was still on it. My specialist changed, so have been on HU since Jan, this year. Very tired all the time, have several side effects, but they could be diabetic related. Got both at same time. Apparently you should be on HU before Agralyn. Good luck with your journey.