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HER2 non small cell adenocarcinoma stage 4 lines of treatment
Hello this is all very new to us. Husband age 63 and excellent health diagnosed June 2025.
He has minimal symptoms but he is stage 4, Lung non small cell Adenocarcinoma , positive ERBB2 ( HER 2) , PDL 1%, Mets to liver and bone. After 4 cycles of carboplantin, pemetrex plus pembro to be followed by maintenance pemetrex and pembro.
He will have PetScan next week ( 4 cycles have been completed) .
A preliminary CT ( after 2 cycles) showed 20% tumor shrinkage and no new tumors. It seems like rather than continue more cycles of maintenance why not right away start with the meds that are being found very effective for HER 2 ?
Is there documentation showing that the first line is more effective for specifically HER 2 in lung adenocarcinoma?
Thank you.
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@rlf66 do you know what type of lung cancer you have yet? if you are newly diagnosed, this video about what to know/ask your oncologist might be helpful for you.
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1 Reaction@mamajite . I do NOT now which type of cancer I have. Having a problem getting any answers from my oncologist. She was to talk with me Tuesday. NO answers as of now. I have left several messages and her M.A. is not returning my calls. Dr. will be off on Monday. I guess I should try a second opinion from another source??
Thanks,
rlf66
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1 Reaction@rlf66 yes, you can seek a second opinion in parallel with your initial diagnosis. I'm not sure where you are receiving care, but I would encourage you to meet with an oncologist at an academic cancer center/official NCI-Designated Cancer Center, if possible.
https://www.cancer.gov/research/infrastructure/cancer-centers/find
@mamajite
Thanks so much.
rlf66
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2 Reactions@rlf66 you're very welcome - let us know how everything goes.