Trazadone

Posted by sue417 @sue417, Mar 23, 2025

Hi
Wondering if anyone has tried trazadone for their fibromyalgia . It helps sleep, depression and anxiety. I have started with 25mg. It actually has helped my tinnitus.

Interested in more discussions like this? Go to the Fibromyalgia Support Group.

Profile picture for jamesduke209 @jamesduke209

I average about 6-7 hours of sleep daily, sometimes more, and sometimes less. My optimum sleep where I wake up and feel well rested is 8-9 hours, which happens once in a while. I generally don't like taking anything for sleep I'll take a Benadryl 25mg tablet occasionally and that gives me about 7 to 7.5 hours of sleep.Recently I was prescribed trazodone 25mg for sleep, but fear taking it because it's classed as SARI anti depressant and I'm afraid of side effects as I had an extremely bad experience with an SSRI that kept me up all night and made me worse at the time many years ago.I'm thinking since Benadryl 25mg does a decent job maybe I can try Trazodone at 12.5mg?Thanks!

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Naturally, I understand your fear of the trazodone. I think that trazodone is the best medicine that was ever prescribed for me. I was having a horrible time sleeping and had a lot of problems at that time with my husband. After I started the trazodone it was so much better for me. At last I could sleep. I have continued to take trazodone through the years. Give it a try. Yes, you will need to taper off of it when you stop taking it. I believe it is a very safe medicine.

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Profile picture for jamesduke209 @jamesduke209

I average about 6-7 hours of sleep daily, sometimes more, and sometimes less. My optimum sleep where I wake up and feel well rested is 8-9 hours, which happens once in a while. I generally don't like taking anything for sleep I'll take a Benadryl 25mg tablet occasionally and that gives me about 7 to 7.5 hours of sleep.Recently I was prescribed trazodone 25mg for sleep, but fear taking it because it's classed as SARI anti depressant and I'm afraid of side effects as I had an extremely bad experience with an SSRI that kept me up all night and made me worse at the time many years ago.I'm thinking since Benadryl 25mg does a decent job maybe I can try Trazodone at 12.5mg?Thanks!

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I have been prescribed trazodone for years for sleep. Yes it is technically an antidepressant, but it is used off label at low doses to help people fall asleep. I originally used to take 100 mg but due to health issues. I’ve lost a lot of weight in the last year and a half and can only tolerate 50 mg without being very hung over. As others have suggested you should consult your medical professional, but when trazodone is used as an antidepressant, it is taken multiple times a day at much higher doses.
I’m like you I have always needed more sleep. I really need 8 1/2 to 9 hours and waking up and not going back to sleep and getting seven hours of sleep or less doesn’t do it for me.

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Profile picture for jamesduke209 @jamesduke209

I average about 6-7 hours of sleep daily, sometimes more, and sometimes less. My optimum sleep where I wake up and feel well rested is 8-9 hours, which happens once in a while. I generally don't like taking anything for sleep I'll take a Benadryl 25mg tablet occasionally and that gives me about 7 to 7.5 hours of sleep.Recently I was prescribed trazodone 25mg for sleep, but fear taking it because it's classed as SARI anti depressant and I'm afraid of side effects as I had an extremely bad experience with an SSRI that kept me up all night and made me worse at the time many years ago.I'm thinking since Benadryl 25mg does a decent job maybe I can try Trazodone at 12.5mg?Thanks!

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I have found that you can trust trazadone . A remarkable med for sleep. For me it worked for 6 months. It no longer works. I was given Ambien 10. Now I have to stop taking that. It’s too addictive. Diazapam happens to be my drug of choice.

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Profile picture for Susan, Volunteer Mentor @grammato3

@jamesduke209: SSRIs and SARIs have different mechanisms of action and side-effects. SSRIs are rarely used to assist with sleep issues while the latter, although not primarily prescribed for this purpose (depression being the primary) has been found to be effective at lower dosage. Trazodone is one such SARI that can help - at least on an occasional basis - due to the sedating effect it has. It does so by regulating serotonin levels and other brain receptors, including histamine - which OTC Benadryl, the generic name is diphenhydramine, also works to block.

I'm not entirely clear from your question, but if you're considering combining the two: 12.5 of diphenhydramine and 12.5 of Trazodone the short answer would be that's not advisable as it could lead to increased drowsiness and potential other interactions. BUT I'm inclined to think what you're asking is if you can try taking half the dosage of the 25 mg Trazodone. As long as it's a scored tablet you can readily halve, and not a timed-release capsule, that ought to be fine to try to see if it would have the desired effect. However, as with all medications and dosages,, your best bet, as @jc76 stated, is to confirm with the provider who prescribed it.

Hope it helps. Can you let me know if you get some good Zzzz's?

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@grammato3 thank you. They never should have taken me off Ambien cold turkey. I’m suffering. Diazapam would help but I have none.

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Profile picture for jamesduke209 @jamesduke209

I average about 6-7 hours of sleep daily, sometimes more, and sometimes less. My optimum sleep where I wake up and feel well rested is 8-9 hours, which happens once in a while. I generally don't like taking anything for sleep I'll take a Benadryl 25mg tablet occasionally and that gives me about 7 to 7.5 hours of sleep.Recently I was prescribed trazodone 25mg for sleep, but fear taking it because it's classed as SARI anti depressant and I'm afraid of side effects as I had an extremely bad experience with an SSRI that kept me up all night and made me worse at the time many years ago.I'm thinking since Benadryl 25mg does a decent job maybe I can try Trazodone at 12.5mg?Thanks!

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@janetfree
Several years ago was really struggling with PTSD anxiety/panic disorder. My ability to sleep was non existent.

My phychiatric specialist prescribed ambien but it did not work. She then put me on Trazodone. It did work. For me it kept my mind from racing to one subject to another. KInd of put a brake on it and went to sleep.

I have been on trazondone for a couple of years now as with other medications and some life style changes (exercising) have improved my condition along with the serious issue I was under at the time.

No medication is going to work the same for every person. It is why don't give up but keep trying to find one that works. But from my experience never stop a medication without going through your doctors. Some require you to slowly come off a medication or you can have side affects.

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Profile picture for razorsharp @razorsharp

grammato STOP doing research on your medication all the time, it does not help you. If your Dr put you on them & you wish to find out more ask your Dr. beside just by taking a few pills for a short time is not going to cause any problems
we all take med of some sort and yes lots of med are not always good but with out trying them first you won't know. but first ask your Dr he should be able to help you there but Stop doing research all the time

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@razorsharp actually, taking lorazepam for just a month has caused me all kinds of problems; I wish my doctor would’ve explained more about benzos before he put me on the course of treatment. Now I’m tapering off for two weeks. But while taking it, it caused more anxiety, even though it’s supposed to calm me down and it didn’t help me sleep all the time either, plus left me pretty groggy and lethargic much of the day. So it does help to do a little research and then you can ask intelligent questions of your PCP.

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Profile picture for razorsharp @razorsharp

grammato STOP doing research on your medication all the time, it does not help you. If your Dr put you on them & you wish to find out more ask your Dr. beside just by taking a few pills for a short time is not going to cause any problems
we all take med of some sort and yes lots of med are not always good but with out trying them first you won't know. but first ask your Dr he should be able to help you there but Stop doing research all the time

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@razorsharp totally disagree. As a patient you need to be your own best advocate. Doing research using reputable sources (like Mayo or Cleveland clinic) is invaluable. Doctors and pharmacists are not experts on everything.

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Profile picture for jc76 @jc76

@janetfree
Several years ago was really struggling with PTSD anxiety/panic disorder. My ability to sleep was non existent.

My phychiatric specialist prescribed ambien but it did not work. She then put me on Trazodone. It did work. For me it kept my mind from racing to one subject to another. KInd of put a brake on it and went to sleep.

I have been on trazondone for a couple of years now as with other medications and some life style changes (exercising) have improved my condition along with the serious issue I was under at the time.

No medication is going to work the same for every person. It is why don't give up but keep trying to find one that works. But from my experience never stop a medication without going through your doctors. Some require you to slowly come off a medication or you can have side affects.

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@jc76
@jc76 replying to @jc76. I am reading my post and as usual I make spelling errors or miss typed something.

Where you read on my post "I have been on trazondone for a couple of years now." It should have read OFF not on. Hope that mistake did not cause confusion with context of my post.

@jc76 you need to proof read your post. @jc76 okay @jc76 will try to do better. 🤢

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Profile picture for jc76 @jc76

@jc76
@jc76 replying to @jc76. I am reading my post and as usual I make spelling errors or miss typed something.

Where you read on my post "I have been on trazondone for a couple of years now." It should have read OFF not on. Hope that mistake did not cause confusion with context of my post.

@jc76 you need to proof read your post. @jc76 okay @jc76 will try to do better. 🤢

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@jc76 Why did you discontinue Trazodone?

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Profile picture for jamesduke209 @jamesduke209

I average about 6-7 hours of sleep daily, sometimes more, and sometimes less. My optimum sleep where I wake up and feel well rested is 8-9 hours, which happens once in a while. I generally don't like taking anything for sleep I'll take a Benadryl 25mg tablet occasionally and that gives me about 7 to 7.5 hours of sleep.Recently I was prescribed trazodone 25mg for sleep, but fear taking it because it's classed as SARI anti depressant and I'm afraid of side effects as I had an extremely bad experience with an SSRI that kept me up all night and made me worse at the time many years ago.I'm thinking since Benadryl 25mg does a decent job maybe I can try Trazodone at 12.5mg?Thanks!

Jump to this post

I took Trazadone - as needed - to help with sleep for years. I found it to be very mild, just helped me go to sleep and stay asleep with little to no grogginess in the morning. Of course, everyone is different. Go to Drugs.com and do a drug interaction check on Traz and your current meds; you can also access the information on side effects there.

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