← Return to Prolia treatment for osteoporosis: What is your experience?

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@harper2018

I have received one injection of Prolia and I am struggling with constipation to the point where I am not willing to continue with the Prolia. My doctor dismisses constipation and back pain as non side effects of Prolia. I have had long standing constipation uses d/t taking an antidepressant, hypothyroidism, statin drugs. I have seen a gastroenterologist with suggestions for fiber. Fiber makes it worse. I am taking miralax. Has anyone else suffered from this?

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Replies to "I have received one injection of Prolia and I am struggling with constipation to the point..."

@harper2018 yes, severe constipation and bloating. Always uncomfortable. The last two and a half weeks before my third injection was the first time I started feeling sort of normal again. Then I got the injection (6 months and two weeks after the 2nd) and all the trouble back again. Totally dependent on laxatives. I have always had an irritable bowel but since the Prolia there are no good days. Also have started with pain around the sternum and clavicle area (cardiac ruled out, no fractures). Some of the discomfort is from acid reflux but mostly feels muscular. Have call in to endocrinologist. My bone density has improved significantly but the side effects are now becoming too unpleasant.

@harper2018 just reading your 2year old post and cant remember if I asked you before. What did you do about treating your osteoporosis? I've had 3 prolia injections and as I've mentioned on this site too many times, my most unpleasant side effect is severe constipation, (always had this problem but nothing like this). I have since the Prolia become laxative dependent. 4th injection coming up in July or Reclast. What did you end up doing?