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Anyone take new drug Camzyos (mavacamten) for HCM?
Hypertrophic Cardiomyopathy (HCM) | Last Active: 7 hours ago | Replies (875)Comment receiving replies
@jess51 @memphis901 @peggykmitchell, gene mutations and family genetics can sometimes be used interchangeably, but they are distinct.
Hypertrophic cardiomyopathy (HCM) usually is caused by changes in genes that cause the heart muscle to thicken. It is often inherited, called familial HCM. People with one parent with hypertrophic cardiomyopathy have a 50% chance of having the gene change that causes the disease. Not all genetic mutations causing HCM are familial. However, genetic testing or genetic counseling may be recommended if you have a family history of the condition.
Further reading from
- Mayo Clinic https://www.mayoclinic.org/diseases-conditions/hypertrophic-cardiomyopathy/symptoms-causes/syc-20350198
- Is Hypertrophic Cardiomyopathy Always a Familial and Inherited Disease? https://www.ahajournals.org/doi/10.1161/JAHA.122.028974
In this Q&A with Mayo Clinic's expert, Steven J. Lester, M.D., talks about hypertrophic cardiomyopathy (HCM) and genes.
Replies to "@jess51 @memphis901 @peggykmitchell, gene mutations and family genetics can sometimes be used interchangeably, but they are..."
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Thank you for the information. I have done some genealogy in the past and
recall both of my mother's maternal grandparents dying fairly young. I then
realized that one of their sons had three sons, all of whom died young,
with two of them definitely having heart issues, although I am not sure
what happened with the oldest son. Then, I found other cousins descended
from those grandparents who had died in their 40s, although one died of
cancer. So, I am thinking there may be a familial gene mutation, but I need
more information to determine that. I like to KNOW about things and so I
like to solve family "mysteries". Thanks, again.