Repatha reaction?

Posted by rhondafunnygirl @rhondafunnygirl, Dec 27, 2024

I’ve been on Repatha for two doses. Out of nowhere started to feel a flutter in bottom of throat or neck. And then a dry cough. Thought it was acid reflux but my gastroenterologist said no and suggested I take magnesium twice a day as my rhythm is slightly off. Has anyone had this reaction to Repatha? I don’t know what to do next.

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Profile picture for cawiegand @cawiegand

I took my first dose 6 days ago. I threw away the second dose as the side effects so far are horrible. I have genetic familial hypercholesterolemia for 40 years now. I am unable to take statins due to side effects. I have one stent and last screening shows minimal blockage. Rapatha is not the way for me. For the last 5 days I can barely walk due to the joint pains in my legs, ankles, and feet. My back hurts like no other and I have had two back surgeries. The injection has exasperated my asthma. I am extremely light headed and lastly this has increased my blood sugar levels like no other. I will be calling my PCP as my cardiologist is not the easiest person to get a hold of and I refuse to pay the money for an ER visit. I am very happy to have found this blog, makes me not second guess my symptons and know that I am not alone. Can anyone tell me when the symptons will calm down and go away?

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As a follow up, I had to take the next day off work due to the light headedness, exasperated asthma issues and muscle and joint pains. How long does it take for this horrible medicine leave my body? I don't like these side effects whatsoever!

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The half-life of Repatha is about 12 days, plus or minus depending on the individual. So, you can expect to have some reactivity, including negative, for up to three weeks, depending on the dose and on your sensitivity to the drug.
https://www.drugs.com/medical-answers/long-repatha-side-effects-3551518/

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Profile picture for cawiegand @cawiegand

I took my first dose 6 days ago. I threw away the second dose as the side effects so far are horrible. I have genetic familial hypercholesterolemia for 40 years now. I am unable to take statins due to side effects. I have one stent and last screening shows minimal blockage. Rapatha is not the way for me. For the last 5 days I can barely walk due to the joint pains in my legs, ankles, and feet. My back hurts like no other and I have had two back surgeries. The injection has exasperated my asthma. I am extremely light headed and lastly this has increased my blood sugar levels like no other. I will be calling my PCP as my cardiologist is not the easiest person to get a hold of and I refuse to pay the money for an ER visit. I am very happy to have found this blog, makes me not second guess my symptons and know that I am not alone. Can anyone tell me when the symptons will calm down and go away?

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@cawiegand I have the same symptoms with my joints, legs, and back. I took 2 shots before I made the connection to Rapatha being the culprit. My last shot was on 8/30 and the side effects are making it very hard to do anything. Can you please let me know if your side effects have subsided, since you are a month ahead of me?

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Profile picture for mrkoos @mrkoos

@cawiegand I have the same symptoms with my joints, legs, and back. I took 2 shots before I made the connection to Rapatha being the culprit. My last shot was on 8/30 and the side effects are making it very hard to do anything. Can you please let me know if your side effects have subsided, since you are a month ahead of me?

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@mrkoos as of today, Sept 26th, most side effects have disappeared finally. I still have some mild joint issues, but not near as bad as it was and my leg spasms have all gone away. My sugar levels are coming down as well. That was a horrible experience! Be patient as they do go away. My best to you.

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I just took my first dose of Repatha on Sunday. I woke up Monday morning with diarrhea, but as someone with severe constipation I was actually thrilled, I figured it was from eating one of my trigger foods, didn’t connect it to the drug. I took a fall in May and have had back pain on and off since then, so when by back began hurting yesterday, again, I didn’t attribute to Repatha. Thank you for pointing out that this drug could be the culprit.

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I've just stopped taking Repatha without my doctor's approval after taking it for a year . She thinks I'm jumping to conclusions but I've been down this road b4. When I was given statins and developed incredibly severe leg pains I was told it was unrelated until the pain was so bad I couldn't work anymore. I stopped the meds & the pain went away. So then I went through all the statins & still experienced either extreme muscle or joint pain. I have familial hyperglycemia which killed my dad at 61. I thought Repatha would be great. The result was much lower bad lipids but my triglycerides and blood sugar went up. As time went on the joint pain which started as a twinge became very severe. I can't stand more than a minute now. I feel like I'm 110 yrs old trying to get up out of a chair. The intestinal issues started small but with time got worse and worse. So I was prescribed more meds and PT to try to counteract all these side effects. Now that I've stopped Repatha the side effects are slowly improving. I'm glad this drug works for some people but it's really terrible to suffer all these side effects every day. I know I am running the risk of a cardiac issue but then I'm trading that for less pain, stiffness and terrible intestinal issues every single day. If you have symptoms, don't let your doctor tell you you're imagining it.

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Profile picture for reillyg1013 @reillyg1013

I just took my first dose of Repatha on Sunday. I woke up Monday morning with diarrhea, but as someone with severe constipation I was actually thrilled, I figured it was from eating one of my trigger foods, didn’t connect it to the drug. I took a fall in May and have had back pain on and off since then, so when by back began hurting yesterday, again, I didn’t attribute to Repatha. Thank you for pointing out that this drug could be the culprit.

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@reillyg1013 I thought when my diarrhea started it was from something I ate or an intestinal bug. Just be wary if the incidence of it starts to get more frequent. I ended up buying a LOT of Immodium before I made the connection with Repatha.

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Profile picture for funnylady @funnylady

@reillyg1013 I thought when my diarrhea started it was from something I ate or an intestinal bug. Just be wary if the incidence of it starts to get more frequent. I ended up buying a LOT of Immodium before I made the connection with Repatha.

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@funnylady I truly appreciate the information, certainly didn’t get any from my doctor. ☹️

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