Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Posted by dougs72 @dougs72, Jun 22, 2024

Has anyone ever been on Duloxetine (Cymbalta) for nerve pain? I've had 2 doctors push this on me. I know that the side effects can be terrible and getting off of it difficult as it requires titration. One time I remember taking one pill, and not liking the way it made me feel, so not taking any more, and still feeling the "weirdness" from it 2-3 days later. and that was only 30 mg Please pass along any experience or advice from this medication?

Interested in more discussions like this? Go to the Chronic Pain Support Group.

i have tried lyrica, gabapentin and i am now on dulexotine. my doctor just upped my dose to 90mg and it was working for me and now i think my body has gotten used to it and i am in severe pain again and muscle stiffness i am taking the dulexotine with lorazepam. the lorazepam helps me sleep at night at least. i am undiagnosed and am coming to the mayo clinic next month but for nerve pain nothing has worked for me not even pain medicine.

REPLY

I just stopped Duloxetine 20mg after two days because of anxiety and muddled thinking among other things. My rheumatologist prescribed it, but I have chronic pain, not nerve pain. I don't know why he prescribed it for me.

REPLY
Profile picture for misspin @misspin

Duloxatine is not for me. The side effects were such that I was instructed to come off, in a managed way.
I haven't resolved the question of what I can take instead.

Jump to this post

I stopped Duloxetine after only two days of 20mg. Side effects were terrible.

REPLY

I’ve taken it for years with carbamazepine and it helps take the edge off. I’ve just discovered magnesium lotion which is helping my numbness in my feet. I’m going to try a medical grade substance with an atomizer when the lotion runs out.

REPLY

I used it for 3 months. It worked great and then stopped.
Ketamine has worked the best for my fibromyalgia and peripheral neuropathy pain. I can’t afford the IVs so now I use compounded sublinguals.

REPLY

Eli Lily has stopped making Cymbalta. The generic is available. I have neuropathy and have been taking 120 mg/day many years. I went through withdrawal from gabapentin many years ago and that was brutal. I’m very concerned about not having the drug that helps with the pain. I’m worried about withdrawal. I get no benefit from the generic and wonder what is working for people now that we can’t get Cymbalta.

REPLY
Profile picture for fredbill @fredbill

I’ve taken it for years with carbamazepine and it helps take the edge off. I’ve just discovered magnesium lotion which is helping my numbness in my feet. I’m going to try a medical grade substance with an atomizer when the lotion runs out.

Jump to this post

Can you let me know what magnesium lotion you use?

REPLY
Profile picture for lovetogarden @lovetogarden

Eli Lily has stopped making Cymbalta. The generic is available. I have neuropathy and have been taking 120 mg/day many years. I went through withdrawal from gabapentin many years ago and that was brutal. I’m very concerned about not having the drug that helps with the pain. I’m worried about withdrawal. I get no benefit from the generic and wonder what is working for people now that we can’t get Cymbalta.

Jump to this post

I guess I am lucky that it still helps me?! I have had 2 back and 1 neck surgery and my neck is really hurting for several years now. My original neck op was in 2011. I have been told to have another one but it would be much more extensive, approach from the back of my neck/head. I also didn’t feel comfortable with potential risks because of how many levels, etc.

REPLY
Profile picture for wisco50 @wisco50

I guess I am lucky that it still helps me?! I have had 2 back and 1 neck surgery and my neck is really hurting for several years now. My original neck op was in 2011. I have been told to have another one but it would be much more extensive, approach from the back of my neck/head. I also didn’t feel comfortable with potential risks because of how many levels, etc.

Jump to this post

I have used Cymbalta in the passed, its the only med that lower my feet pain caused by neuropathy, but that's not my story. I went in for back surgery, they started to put me out , before first cut, I had cardiac arrest, 3 session of cpr to get heart going again.I feel what happened to me was they had mixture of fentanyl in anesthesia which caused serotonin syndrome. Dr's would not confirm this.after release from hospital check on drugs.com is there any interaction between Cymbalta & fentanyl the answer was a big yes, it can cause cardiac arrest. I have been put out since several time,I always tell my story first with the interaction of the 2 drugs so they always make sure i have no fentanyl in there mixture. Needless to say I no longer take Cymbalta even tho it helped with pain.Its a different story how to wein yourself off of Cymbalta, Good luck on future surgery

REPLY

I was on hydrocodone , Gabapentin and Duloxetine and take Sunosi to keep me awake which doesn’t help! I stopped the hydrocodone to see if the worthless pain stimulator was helping( nope it was actually causing pain enough that we discussed adding a second one for the sacrum) . I’ve taken Gabapentin 100mg morning and 300 mg at night for a couple years. I couldn’t tolerate stronger because of sleepiness. Withdrawals weren’t bad then 2 weeks later pain doc had me stop Duloxetine I was taking 60 mg and still had some 30 mg stool a 30 mg a couple nights. I noticed withdrawals were diarrhea got that and I’ve had Tinnitus but after reducing the pills I have now stopped them but now have a new sound that’s hard to explain kind of like a ch ch ch . If pain comes back he discussed a causal epidural or after that a pain pump. If you have a stimulator and have unexplainable headaches ( I was hospitalized 5 days for temporal headaches that they couldn’t figure out I came home and turned the stimulator off and the headaches went away so keep this in mind

REPLY
Please sign in or register to post a reply.