After two regiments of Xifaxan my wife's latest breath test came back negative for SIBO. The problem is that she is still suffering from chronic nausea. She will eat a piece of toast and a cup of tea for breakfast and will be nauseated within fifteen minutes accompanied at times by violent belching and regurgitation. Her latest visit to the ER, and subsequent admission, once again found no abnormalities in her tests. The hospital could not duplicate her sever nausea on a hospital diet, but as soon as she got home the nausea reappeared. It is disappointing that the SIBO test was negative, because a positive reading would have at least given a diagnosis that could be treated. There have also been some suggestions that her symptoms might be psychosomatic. I would appreciate any feedback from anyone who may have had such symptoms. Tuesday she has an appointment with the gastroenterology consulting physician who seen her in the hospital. This will be the fourth GI physician she has had in the last four years.

Have they tried any other antibiotics? I found that some antibiotics worked for me, while others did not. Xifaxan did not work for me.

I too got negative results from a breath test, but had SIBO diagnosed through intestinal aspirates. Apparently breath tests are not always accurate. Is your wife's GI physician at the Mayo Clinic? Before visiting the Mayo Clinic in Minnesota, I was undiagnosed and misdiagnosed by 4 different GI doctors. They were all great physicians at reputable hospitals, but they all just missed something.

What did they miss? Her GI doctors are not at Mayo.

Yup, my breath test was negative also. In fact I think every test I ever had done was normal. I have an underlying autoimmune disorder which contributes to G.I. dysmotility though

I was diagnosed with SIBO, EPI, and small bowel damage (partly caused by the bacteria, and partly caused by a birth defect). I suffered with chronic diarrhea, nausea, vomiting, and weakness for over 20 years. I had multiple endoscopies, colonoscopies, blood tests, MRI's, CT scans, fecal analysis, allergy testing, and so on. My last GI doctor referred me to the Mayo Clinic because he would not accept that even though every test was "normal", there was something very wrong. The GI doctor at the Mayo did an endoscopy at my first appointment, and found everything that he needed to from that. Why no one else could find the source of my problems from the past endoscopies I'd had is baffling.

Sounds awful, I am glad they have found the source of your problems now though. So how are they treating your SIBO?

After leaving the Mayo in November, I went through a round of Diflucan, Flagyl, and Cipro. That's it! The GI doctor at the Mayo said that was all I needed to do, and then take a daily probiotic. He strongly recommended Align, so that's what I take. I guess the bacteria is gone? I sure feel like it is, at least for now. I no longer have excessive gas, bloating, stomach pain, indigestion, diarrhea, vomiting, etc. Of course, SIBO wasn't my sole diagnosis, so some of my symptoms could've been related to other issues. Anyway for now I feel great. If at any point I have recurring symptoms, I was told to contact my Mayo GI doctor, and he'd reassess my situation.

Glad you managed to find some answers. 20 years is a long time!

<br>How do I get appointment with GI at the Mayo Clinic?<br><br>Thanks<br>Virginia <br>