Pat, In the past, I had afib severe. Then last year started up again. It was caffeine and only takes less than one half cup coffee from the US. But never took Eliquis, and never will. I have learned to never take meds without investigating the side effects first and end up taking none. I search for the root cause, and do what I can to eliminate that. And if you have GI upset or indigestion, examine what and what combinations you are putting down the hatch. I am 77 this month and have greatly changed little by little what I eat the last 50 years, and rarely have any indigestion, but in the past was doubled over in pain, or full of gas bubbles for hours.