Have you tried this treatment? Stellate Ganglion Block study

Article: Cureus | Stellate Ganglion Block Relieves Long COVID-19 Symptoms in 86% of Patients: A Retrospective Cohort Study | Article

DEFINITIONS:

Stellate Ganglion Block (SGB): a procedure where anesthetic is injected near the stellate ganglion, a group of nerves in the neck, to relieve symptoms such as pain or nerve dysfunction.

SUMMARY:

The study evaluated the use of stellate ganglion block (SGB) in the treatment of long COVID-19 syndrome.

Out of the 41 patients who received SGB, 86% experienced a reduction in their symptoms.

The most frequently reported symptoms were fatigue and brain fog, which showed the highest response to treatment.

My take: (by Amy E - contributor to the newsletter)

This is what I had done and it has been the biggest game-changer out of all the things I’ve tried!

Interested in more discussions like this? Go to the Post-COVID Recovery & COVID-19 Support Group.

Profile picture for pillpd01 @pillpd01

Thank you. That was very helpful

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Interesting results! I, too, have uncontrollable blood pressure and tachycardia. and now COVID-induced asthma. Cardiac workup shows nothing (heart monitor and echocardiogram).
I haven't finished my lung workup (cardiac workup was required to rule out before lung workup), but I suspect the same.

After some research, I read an article NIH published regarding the vagus nerve and parasympathetic system upset directly attributable to COVID. There are thousands of recommended exercises (simple and free) that I have been seriously undertaking (in the last week). I have made significant progress in getting this under control. So much so, will soon ask for a 1/2 reduction in both BP and HR meds if this trend continues for the next 2 weeks. I looked at the ganglion block, but because I'm still not through the lung testing, I'm a ways out from any such treatment. Keeping it in my back pocket just in case.

When I initially had COVID, I read about using lavender oil to retrain my brain to smell. I completed the recommended process, and my sense of smell slowly returned in three weeks. Not sure if a direct correlation, but I was happy when my sense of smell returned. I don't believe I have any smell loss - 6 months past the initial infection.

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Profile picture for dmphillips @dmphillips

Interesting results! I, too, have uncontrollable blood pressure and tachycardia. and now COVID-induced asthma. Cardiac workup shows nothing (heart monitor and echocardiogram).
I haven't finished my lung workup (cardiac workup was required to rule out before lung workup), but I suspect the same.

After some research, I read an article NIH published regarding the vagus nerve and parasympathetic system upset directly attributable to COVID. There are thousands of recommended exercises (simple and free) that I have been seriously undertaking (in the last week). I have made significant progress in getting this under control. So much so, will soon ask for a 1/2 reduction in both BP and HR meds if this trend continues for the next 2 weeks. I looked at the ganglion block, but because I'm still not through the lung testing, I'm a ways out from any such treatment. Keeping it in my back pocket just in case.

When I initially had COVID, I read about using lavender oil to retrain my brain to smell. I completed the recommended process, and my sense of smell slowly returned in three weeks. Not sure if a direct correlation, but I was happy when my sense of smell returned. I don't believe I have any smell loss - 6 months past the initial infection.

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My wife Diana has had LC for about 3 years. After the usual struggles finding a Dr that would work with her we found a PCP that was willing to try Prendisone. The course of treatment did help but didn't provide significant improvement. Last fall while reading this blog I found the sections regarding using the Stellage Ganglion Block as a treatment. We researched it and found several small studies (40-50 participants) that showed benefits from the SGB. After discussing it Diana said she wanted to try it. Her PCP was willing to give her a referral to the local Pain Clinic and we met with a Dr there that was willing to try the procedure to see if it would help. On 3/27/25 she had a single shot on the right side performed. The results have been very good. I have been logging each of the first 10 days and how it has gone. I will attach that log to this site.

Please note, we are NOT doctors and this isn't medical advice. It is however a personal account of a treatment she tried that has helped her as an individual. This treatment isn't a cure all but for LC sufferers it is something to be looked at. I wonder if it is more helpful if your symptoms fall more into the autonomic nervous system categories than others?

Shared files

Stellate Ganglion Block Results with Long Covid (Stellate-Ganglion-Block-Results-with-Long-Covid.pdf)

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Profile picture for oldhiker73 @oldhiker73

My wife Diana has had LC for about 3 years. After the usual struggles finding a Dr that would work with her we found a PCP that was willing to try Prendisone. The course of treatment did help but didn't provide significant improvement. Last fall while reading this blog I found the sections regarding using the Stellage Ganglion Block as a treatment. We researched it and found several small studies (40-50 participants) that showed benefits from the SGB. After discussing it Diana said she wanted to try it. Her PCP was willing to give her a referral to the local Pain Clinic and we met with a Dr there that was willing to try the procedure to see if it would help. On 3/27/25 she had a single shot on the right side performed. The results have been very good. I have been logging each of the first 10 days and how it has gone. I will attach that log to this site.

Please note, we are NOT doctors and this isn't medical advice. It is however a personal account of a treatment she tried that has helped her as an individual. This treatment isn't a cure all but for LC sufferers it is something to be looked at. I wonder if it is more helpful if your symptoms fall more into the autonomic nervous system categories than others?

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Thanks. This is great information

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Profile picture for oldhiker73 @oldhiker73

My wife Diana has had LC for about 3 years. After the usual struggles finding a Dr that would work with her we found a PCP that was willing to try Prendisone. The course of treatment did help but didn't provide significant improvement. Last fall while reading this blog I found the sections regarding using the Stellage Ganglion Block as a treatment. We researched it and found several small studies (40-50 participants) that showed benefits from the SGB. After discussing it Diana said she wanted to try it. Her PCP was willing to give her a referral to the local Pain Clinic and we met with a Dr there that was willing to try the procedure to see if it would help. On 3/27/25 she had a single shot on the right side performed. The results have been very good. I have been logging each of the first 10 days and how it has gone. I will attach that log to this site.

Please note, we are NOT doctors and this isn't medical advice. It is however a personal account of a treatment she tried that has helped her as an individual. This treatment isn't a cure all but for LC sufferers it is something to be looked at. I wonder if it is more helpful if your symptoms fall more into the autonomic nervous system categories than others?

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I wanted to post a followup on Diana's status about 1 1/2 months after her first SGB treatment. So far the treatment has been durable, her fatigue and PEM have been signicantly reduced. She is now walking 1.3 miles a day and not having signifcant crashes. Brain fog is still present in short term memory but other congitive function (working with her cell phone, starting to do jigsaw puzzles again) have been better. Less prevalent symptoms like GI issues and sleep disturbances have been better also. A quote from Diana " I feel like it has given me my life back".

I am NOT a doctor but have researched the information on the web and seen the results first hand. If you are having symptoms that may fall under the Neurological grouping or have Dysautonomia, please check out this treatment. There are Pain Clinics around the country that are offering this as a "off label" treatment. In our case I would like to thank the Interventional Pain Managment Clinic in Mountain Home Arkansas for being willing to let Diana try this treatment, it has been a game changer for her. I will try to post a link below to a web video where a Dr discusses using the SGB for PTSD and LC. Check it out.
https://lebtown.com/2024/12/05/dr-michael-fishman-introduces-innovative-treatment-for-ptsd-and-long-covid-with-stellate-ganglion-block-therapy/

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Profile picture for froggiiii @froggiiii

North Shore (now EndeavorHealth) has a large Pain Management clinic in Skokie Illinois. I'm had two Stellate Ganglion Blocks +Sep and Dec 2023) with a 3rd scheduled for March 2024. They helped reduce headaches, reduce body sensations and improved sleep. Not helpful for fatigue in my case. Covered by Medicare. Took months to get initial appointment.

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Hi. I had the stellar ganglion block in California but wasn’t able to have insurance cover it. Would you share what diagnosis code they used for coverage? It was quite expensive.
It did help with brain fog, exhaustion and heart palpitations. Also digestion is better. I think I will need another time to optimize the results.
Thank you

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Profile picture for lauragwi @lauragwi

I have had four SGBs now. The first (right side) helped significantly with my lungs and upper chest tightness. After 3 years of long-COVID, within 24 hours of block, could take a deep breath for the first time. I had to learn to breathe again because I had tight chest for so long, having that suddenly lifted felt weird. I have since had a left side 6 months after the first, and a left and right spaced two weeks apart two months ago (8 months after the second). The subsequent blocks have not helped as much. My fatigue is still the same, maybe some very moderate relief but only two weeks after. My episodes of intense symptoms are shorter now, but not sure if that is from blocks or just passing of time. For whatever reason, the blocks on the right side helped and the ones on the left did nothing.

I had to fight to get insurance to cover, but I connected with a non-profit healthcare/patient advocacy group to help and compiled a letter citing research on SGB and explaining their is no FDA approved treatment, so by denying me because SGB is experimental, they are denying me all treatment for long COVID because all is experimental. Overall it is very worth a try in my book!

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Hello, are you able to share more on how you got insurance to cover it for long COVID? I have had some success with the treatment but will need more and it is very expensive. Almost four years of this and after the injections I woke up and thought “wow, it’s me. “
Thank you

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Profile picture for kt8 @kt8

Hello, are you able to share more on how you got insurance to cover it for long COVID? I have had some success with the treatment but will need more and it is very expensive. Almost four years of this and after the injections I woke up and thought “wow, it’s me. “
Thank you

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Getting insurance to cover SGB was a pain. Basically you have to make a compelling case that the treatment is medically necessary. I cited some case studies showing initial promise of the treatment (I listed them below - but there are likely more up-to-date ones now). I explained how there are no FDA approved treatments for long-COVID, so everything is experimental at this point (my initial denial was due to it being experimental).

In your case, I would include your testimony plus that of your physician's on how the treatment has helped. Generally when used for chronic conditions, you need SGBs every so often (my provider said you had to wait a minimum of 3 months; I tend to go 5 to 6 months in between before needing it for my lungs). So try to find some evidence about that, whether for long-COVID or not, and include that too.

Finally, I worked with a health advocacy non-profit to help with my appeal to insurance. You should be able to call your local United Way to see if such a service exists in your area.

Hope this advice helps...best of luck!

Here are the studies I cited in my insurance appeal (but that was 2+ years ago so these are somewhat out of date):

1. “ Know Your Treatment Options for COVID-19”. https://www.fda.gov/consumers/consumer-updates/know-your-treatment-options-covid-19
2. “Stellate Ganglion Block”. https://my.clevelandclinic.org/health/treatments/17507-stellate-ganglion-block
3. “Stellate Ganglion Block Successfully Treats Long COVID/PASC: A Case Series”. https://assets.researchsquare.com/files/rs-873830/v1/80a84314-a831-4ee8-bd3e-cc6501beda46.pdf?c=1631889297
4. “A Review of Stellate Ganglion Block as an Adjunctive Treatment Modality”. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029323/
5. “Stellate Ganglion Block for Long COVID Symptom Management: A Case Report”. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822527/
6. “Stellate ganglion block reduces symptoms of Long COVID: A case series”. https://www.sciencedirect.com/science/article/pii/S0165572821003118

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Profile picture for kt8 @kt8

Hello, are you able to share more on how you got insurance to cover it for long COVID? I have had some success with the treatment but will need more and it is very expensive. Almost four years of this and after the injections I woke up and thought “wow, it’s me. “
Thank you

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The only direct diagnosis was this text "sympathetically maintained pain" for the information associated with this procedure.
I also have the following on my chart. It only shows text, not the codes.
Weakness
Other fatigue
Primary hypertension (started with Long COVID).
Post-COVID chronic fatigue
Procedure codes as follows:
HB INJ CERVICAL SYMP NERVE BK [64510 CPT(R)]
HB PAIN INJECTION PROC TRAY [80008268 Custom]
HB US GUIDE NEEDLE PLACE BIOPSY ASP/INJ/LOC S&I [76942 CPT(R)]

Good luck. At this point, probably not related to any medical procedures but simply time, my remaining issue continues to be fatigue.

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