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Lupron yeah or Lupron nay that is the question.
I've rationalized my need for Lupron Therapy. But there are holes in my analysis. The holes are there because of lack of data. So I'm in search of data. I want to hear the real data on the pros and cons of Lupron. All I have heard are generalities. Nothing specific, nothing quantatative, so let's get real.
I invite all to participate including moderators as this is relevant to all and also beneficial to all. My initial query. Who, what facility, has my Lupron answers? They have to be there else we would not be using that form of therapy. It had to have been researched into oblivion as are all procedures in the US of A thus justifying their cost structuring. When does Lupron cease to be effective? That is, what quantifiable condition of our tumors renders Lupron useful? If your doctor says you are cured of your cancer then why continue it's use? If it ain't broke why "fix" it??
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While on Lupron I went anemic big time. Lipids remained fine. Fatigue, shrinkage both areas, 1 grade 1 hot flash and lower energy were my side effects. Changed to Orgovyx after 3 months and most of the same except my anemia corrected itself back into the normal and after 3 months LDL rose on Orgovyx. I had blood work done by primary prior to starting for a baseline, after 3 months showing anemia which really sucked, and one day after stopping ADT at 6 months with higher LDL. Not if this is the normal difference between the two drugs but an interesting comparison.
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1 ReactionCongratulations on your 60th anniversary, amazing!!!
Sorry , why can’t I delete comment?
If you get in there quickly enough, you can edit a comment or reply and remove all the text and just put something in like ABC and it’ll accept it.
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1 ReactionJust a couple things, Jeff. David was on Lupron & Zytiga/Prednisone for the 1st 3yrs & now off ARSI for over a year. He goes every 3mos & now his PSA is the lowest it's ever been, 0.06. They have started him on Eligard & I've read some good things about it, so like I said I have been sold on the ADT, since it doesn't really hurt anything. However, lymph nodes can get inflamed for different reasons & PSAs can spike for different reasons. And also it is still CSPC & BRCA tested negative. We are more interested in quality of life. And I know God will get us thru whatever may come.
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1 ReactionLupron and Eligard Use the exact same drug. They actually ran out of Lupron about four years ago And I had to get Eligard 6 month shots for a year. They actually gave them in the hip right near where the Lupron shot goes. It surprises me that some places give the Eligard Shot in the stomach when that is definitely not necessary.
I have heard that some of the ultra sensitive PSA machines have a minimum of .06, So yours may be the bottom of that machine’s ability.
Yes, infections can inflame lymph nodes, But when you have prostate cancer, it is much more common for cancer to get to them.
As I’ve mentioned after nine years of ADT nobody really sees that I have any problems other than an occasional hot flash. Yes, I have to take bone strengthen yes I have to exercise regularly, but that is really good for somebody that’s 77 years old., And it is good for somebody even if they’re 65. It seems that keeping in good shape can help keep prostate cancer at bay.
Well, PSA can rise for different reasons almost all of those reasons are when you have a prostate. After a prostatectomy, the only reason the PSA rises is because of biochemical reoccurrence, At least I’ve never heard of any other cause.
Thanks for your input. Unfortunately, the pain started three days after my first Lupron shot and have only gotten progressively worse over the last two and a half months. When I called my doctor to voice my concerns, he told me to just take ibuprofen. I've been doing that every day but it only works for a couple of hours. It's much worse in the morning. I can barely function until 2:00 in the afternoon. My next appointment is Sept. 3rd. My guess is he will give me more drugs including Prolia since my cancer has metastasized to my L5 spinal bone.
Ask your doctor to put you on Orgovyx Instead of having a Lupron shot. Orgovyx Is a pill you take every day and if you’re having pain, you could stop taking the pill and see if it makes a difference. With a Lupron shot it’s not that easy.
See if your doctor could put you on Nubeqa. It doesn’t reduce your testosterone and works well to keep the PSA down even though you’re not on ADT.
I must admit, after all these years of listening to people‘s pains getting treatment I have never heard of anybody having so much pain just from ADT.. That’s why you wanna try some other things.
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2 ReactionsOn Lupron for 3 years with little side effect. Held PSA down. Recently had a climbing number. Tests indicate metastatic bone cancer. Xtandi and Xgeva given. Considering next step as it appears Xtandi not being effective. 82 years old. Had 16 years of success after prostate removal.
Has the option to use SBRT radiation on the bone metastasis been discussed? If there aren’t too many and they haven’t damaged the bone much that can stop them from bothering you further. Dr. Scholz In Marina del Rey, can be observed on YouTube discussing this in PCRI videos.
If the bone Mets are too Extensive than chemotherapy or Pluvicto Can give you relief and Extend your life.
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