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Leiden Factor V: Can I use hormone replacement therapy for menopause?
I am heterozygous for Leiden Factor 5, although I haven't had any issues with blood clots so far -I'm 54 yrs old. I'd like to go on hormone replacement therapy (HRT) due to menopause. I've read using an estrogen patch decreases the risk of clots associated with HRT. I'd like to hear if others with Leiden Factor V have used HRT, and if so, if they also went on a blood thinner to further decrease the clotting risk. Thanks!
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@ashley78, I noticed that you wished to post a URL to an article with your post. You will be able to add URLs to your posts in a few days. There is a brief period where new members can't post links. We do this to deter spammers and keep the community safe.
Clearly the link you wanted to post is not spam. Please allow me to post it for you.
- Hormone replacement therapy in women with history of thrombosis or a thrombophilia https://journals.sagepub.com/doi/10.1177/20533691221148036
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1 Reaction@kms1s, please see the comment I posted earlier. The study I mentioned made things very clear for me.
Im a 37 ur old female w factor 5.
7 years ago I had pulmonary embolisms in both lungs. I believe the oral birth control and combined w factor 5...activated me to have clots.
Still on eliquis now and trying to get more info about coming off of it. If it's safe.
Not sure if u like holistic, but if u want to try WELLECO products. It's an auzi brand, natural sourced and I'm taking it for my hormones. It's helped me alot so far.
I was diagnosed with Factor 5 Leiden while in the hospital after suffering a PE that almost killed me. This happened 20 years ago. I was lucky to survive. I have been on blood thinners since then. I am on 15mg Xarelto daily. I am not thrilled about being on a blood thinner but I would rather be safe than die from a PE.
Me too - if I hadn’t fainted would not have gone to ER… It was 2020 July during lockdown- had clots in saddle AND lungs - flummoxed docs since no standard treatment if heparin doesn’t start healing and blood pressure drops… I figure it was just not my time to go. So lucky. Now on Elloquis 5mg 2 x/day. 72 yo now… have Prothrombin + Factor V Leiden mutations … never got pregnant and I’m guessing I was lucky I didn’t or my body resisted to keep me alive.
I was diagnosed estradiol yesterday, but I too am concerned about it's safety. I was diagnosed with Factor V leiden and put on blood thinners about four years ago after having ischemic colitis three different times. They first thought there was some issue with my colon but after colonoscopy and CT, etc. they decided it was a blood clotting problem. Since taking the blood thinners, I haven't had any issues thankfully. I really want to start the HRT, but I am also scared!
I’m going through the same thing. I really feel it would alleviate many of the side effects I’m feeling currently. I was diagnosed with Polycythemia Vera 2 years ago. I’ve never had a blood clot and only take 2 baby aspirin daily. Would love some advice on this!
I do not have what you have but I went back on HRT because of low estrogen and ended up with breast cancer . I would really run this by your doctor. After surviving breast cancer, a lumpectomy, and a month of radiation, I ended up with SMZL, a blood cancer.
I am heterozygous for factor V Leiden. I did have a blood clot in my leg after the birth of one of my children. I opted not to do HRT of any form because the studies are not clear and each person is different. It was a risk I did not want or need!
Thus article is from 2003 and the science has changed. Most of the women used in the studies had co-morbidities. The risks are not dramatically increased particularly with the patch.