Can anyone share their experience with Nubeqa (darolutamide)?

I gave an appt with oncologist on Thursday at 130 praise the Lord 🙏 Againn Danks to.you all.

I've been on Nubeqa since March and have not experienced any side effects other than reduced PSA and Testosterone. Knock on wood. 😉

I have hot flashes with nubeqa. At night I get hot and sweat some even with ac on. I been using a fan and that has helped.

I have been on Nubeqa almost 3 years. I always take it with food and within 1/2 hour of being 12 hours between doses. No digestive problems to report. I do experience some brain fog and weakness but I am also on Lupron every 3 mos and have had chronic lymphocytic leukemia for 20 years so it’s hard to say where my symptoms come from. But the combination of Nubeqa and Lupron have kept my PSA and testosterone levels to virtually zero. Also, my prostate cancer had already spread to my liver and bones when I was diagnosed and I’m still alive and kicking ( thought not as long as I used to).
So , to summarize, Nubequa is helping to keep me alive. That’s worth the side effects.

Are you on shots 2? It may not be my nubeqa making me hot, although I'm on 600mg twice a day

I take a shot every 3 months along with nubeqa. I'm like you I'm thankfully for every day. Do you have any pain anywhere? My psa dropped from 53 to 19.

Wow! Three years. I thought I was long at two years. Started when I did chemo, soon after I started Lupron injections. Stopped Lupron after 13 months. So I’ve been on Nubeqa monotherapy for almost a year. Primary side effects include gynecomastia and fatigue, especially in my legs. My PSA has stayed negligible while my T has risen to 350.

No. Just Nubeqa and Orgovyx. My PSA in February was 32 and testosterone in the 5 hundreds
After one month my PSA was 4.1. Testosterone was 5
In June it was .24 and no detectable Testosterone.
So it seems to be working.
HTH

That's great!!

Is yours metastatic?