My husband was prescribed Pepcid 40mg for acid reflux exacerbations. Because of his age (82) it is a high risk to perform any invasive procedure due to his heart failure and cardiac Amyloidosis. He has been taking Nexium for quite a while and it also has been working well. After starting Pepcid before bedtime he started to get urinary issues. At his fourth day of taking Pepcid he developed urinary retention which he suffered from it years ago. He was self-cathing for a while but the retention stopped. He went to the ER yesterday because of retaining urine (he takes diuretics). Everything was fine, the labs normal but now he is self cathing again. He decided to stop Pepcid after he found out it causes urinary retention especially in the elderly. He wants to see if Pepcid was the cause or not. Has anyone heard or has experienced issues with Pepcid regarding urinary retention?