Rytary is just an extended release version of Sinemet. Rather than 25/100mg it is 50/200mg. My wife who has had PD for 15 years tried Rytary but did not find it helpful for extended symptom relief. She had DBS five years ago and that has provided more steady relief when combined with some medication. She walks a mile a day, bikes, swims, hikes and teaches yoga regularly.

Best wishes, Joe

THANKS JOE