I have been on Camzyos 1 year and a half. I have some difficulty sleeping but not too bad. When I am under stress it is hard to sleep my 7 hours and I can only sleep 4 to 5 hours so I am very misserable those days. In general I tried not to worry about anything so I am able to sleep now 6.5 to 7 hours and I feel a lot better. No other side effects at all. I controlled my weight by walking 2 to 3 miles every single day. I eat very healthy diet now avoiding too many carbs. In general, I have been very lucky to have reduced my septum size from 2.3 cm (my heart almost fully blocked with limited blood circulation) to 1.3 cm all of that in a few weeks but I cooperated by having very strict died and a lot of walking so I lost 20 pounds in only 8 weeks which helped my condition. I am still on Camzyos and since my Medicare covers it in full, I am not planning to be out of it for the rest of my life since all the chest pressure is gone from the 1st week I started that medicine. I am very sorry that Camzyos is not for everyone but I am blessed by God it works really very well on me with almost no side effects other than slight insomnia. That insomnia I learned to control it by trying to be relaxed and happy which is not easy but I am still able to do that. God bless everyone and I hope all will get better of this inherited condition of Hypertrophic Obstructive Cardiomyopathy.