Low dose naltrexone for Post-Covid Recovery experiences?

Are you any better? You sound exactly like me.

After 5 months on LDN, I think I may be a bit stronger. I can sit up after sitting a bit better, but that is all I can tell. My balance, which is my worst problem is no better. It is worth a try. Now I am taking naltrexone plus a couple other anti-inflammatories, but that hasn't helped any. It is the only program I have been recommended so far, so I won't change. I do have another appointment with my original neurologist on Monday, so I will be interested in what he has to say.

I have been using LDN for 5 months, but I cant tell any difference except I am a bit stronger. My main problem is balance however, so I cant say about any other symptoms. It is worth a try. I am up to 9mg per day now.

I’m wondering if it helps to increase the Naltrexone dose?

@meow Dr. Patterson's team has me on LDN total time now about 6 weeks. I was at 1.5 and stepped up to 2.5 and just last night stepped up to 4.5. Dr. Bream (on Patterson's team) told me that 'many people' are going to feel a difference (if it works for them) at 2.5 (like a doorway you step through). At 2.5 I can't say that I felt a difference thus the step to 4.5. We shall see what happens at 4.5. As you likely know, Naltrexone is a drug designed to help people with addictions, but those dosages are north of 20 miligrams so those of us who are trying it are truly Low Dose Naltrexone.

Hello Beachbum, I had thought Dr. P medicated LC patients using only Maraviroc and Lipitor, so why is your doc treating you with LDN? That’s an important issue, I think. Some have reported here that LDN is effective. Others say it’s not. Could you tell us much more about what your doc is thinking about this important issue? I wonder if side effects of the meds play a role here. Incidentally, the docs at Northwestern Medicine in Chicago use only Amantadine and one other - but not LDN, Lipitor or Maraviroc - for LC.

I started LDN after visiting the Mayo Clinic this past April. Suffered my fourth Covid infection last summer (July, 2024) and did not bounce back. Had severe SOB and several episodes of ventricular tachycardia, extreme fatigue, and insomnia, as well as brain fog. Ablation procedure last August stopped the VT, but all the other symptoms continued. Was absolute hell. Could not work. I was lucky to be seen at Mayo Clinic where they ran me through several tests to confirm Long Covid Syndrome. Suggested a handful of meds to try, one being LDN. Started at 1.5mg and am now at 3mg with a target of 4.5mg. I echo what many others have said in that it has improved my sleep and maybe a little improvement with strength/stamina ( I still experience PEM however). SOB and brain fog have not changed due to LDN. Trying to stay positive and patient in giving LDN time to work.

I would recommend not using so many acronyms. I am a 5 year Long Covid person, but don't recognize SOP for example. I too have been on Low Dose Naltrexone for 5 or 6 months and am at 7.5mg dosage currently. I was also reommended to take cysteine and folate. I would say that I am a bit stronger like you mentioned, but I am also no better in my balance / dizziness. I went to Cleveland Clinic and they were very good, but like all doctors, they don't have the answers either.

I too am surprised Dr. Patterson is using LPN. He had some other way to diagnose Long COVID and also to treat it. I have been dealing with Long COVID for 5 years now and have gone to many doctors and read many research reports on this disease, but still have no balance and am dizzy all the time. But, I keep looking for a cure. No one has one yet. I just returned from an appointment with my original neurologist a few minutes ago. Now, he thinks I might have 3PD, which is an abstract problem with no treatment. I used physical therapy for years to no avail. But, I am not ready to give up.

P.S. Maybe, if your symptoms were limited to balance and dizziness problems (not fatigue, brain fog, etc.,) your doc decided to treat you only with LDN. Why not just ask your doc to explain?