I was diagnosed with ET and was referred to the Mayo Clinic in Arizona. After a bone marrow biopsy, chromosome test, and a full abdominal ultrasound, everything was normal except CALR positive, JAK2 negative, but continually elevated platelet counts. I learned my condition is NOT genetic, but rather a DNA mutation common as you age. I am now taking a low dose 500 mg hydroxyurea MWF. But it was reassuring to know everything else was normal. I continue to eat an anti-inflammatory diet and work out at my our local gym to try to stay as healthy as possible. Grateful for the otherwise good health.