Blood in urine after BCG treatment: Is this normal?

Posted by tgsmith @tgsmith, May 24 7:53pm

I had my 6th BCG treatment 9 days ago, for the last 2 days I’ve had bright red blood in my urine has anyone else every had this happen

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I think I've had some, but I'm on a blood thinner, Eliquis. When it seemed certain, I stopped one dose and it stopped the bleeding. Other times, it may have seemed red in the urine, but could have been discoloration from Uribel.

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@vejan738

finished with my 6 BCG treatments and the cystoscope determined it did not work after waiting a month. So now until a new drug that just got FDA approval, buts its very expensive. Clinical trials have taken place and results are impressive after only 1 treatment

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What is that drug, Keytruda?

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@tms3

I think I've had some, but I'm on a blood thinner, Eliquis. When it seemed certain, I stopped one dose and it stopped the bleeding. Other times, it may have seemed red in the urine, but could have been discoloration from Uribel.

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I had blood and was also on blood thinner Eliquis. Paused the BCG treatment one week because of that. Urine sometimes as dark as cabernet wine. After getting my Afib under control, Cardiologist had me stop the blood thinner. Urine eventually cleared up. However, I failed any benefit of BCG. Going for third BC surgery this week followed by Adstiladrin treatments. Hope that works. Cardiologist installed a loop recorder to make sure the Afib stays under control and to (hopefully) keep me off blood thinners.

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Hi allen1947,
Thanks for you feedback. Coincidentally, I've had some bleeding the last two days (BCG 4 days ago), but it seemed to stop this morning. Still, I cut my morning dose of Eliquis in half just for today, The bleeding soon completely cleared up, but is was so fast, I'm not sure just why. Now, I'm wondering what this "loop recorder" is? I too have been taking Eliquis because of afib. In my case, I had a mini-maze and then several ablations and eventually that made it appropriate to get a pacemaker. I can still go into afib so am still on Eliquis. Thus my curiosity about the loop recorder. Sorry you lost the benefit of BCG with the interruption in treatments. I'm coming up to my 6th this next week, and then we'll see. The last two BCG's have been excruciatingly painful and I've got a doc who refused to give me any effective pain meds...just Tylenol and Uribel. Neither is very helpful.

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@tms3

What is that drug, Keytruda?

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It is an immunology IV drug. Generic name is Pembrolizumab. As I understand it, this drug therapy is indicated only if BCG therapy has failed. It is a fairly new drug and has found use for a number of different cancer types: Skin, Hodgkin's lymphoma, lung, head and neck, gastric, esophageal, bladder, colorectal, endometrial, cervical, liver, breast, and kidney, and "may be used for other treatments". For bladder cancer it is specific to "high-risk, non-muscle invasive bladder cancer {NMIBC} and when...it is a type called "carcinoma in situ (CIS)". Another, Anktiva, I don't understand much, but apparently is used WITH BCG with the same intravesical injections to enhance the effectiveness of BCG. I've had to find this out on my own as it has not been mentioned but any of my doctors.

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