Recurrent Vaginal Cancer

Posted by warrior2225 @warrior2225, Jun 13 12:58pm

Hi everyone, I had stage 3 vaginal/lymphnode cancer in 2022. I had chemo, radiation and brachytherapy. I was in remission until May 2025. The vaginal
cancer came back. My Oncologist told me I cannot have more radiation or chemo. He also told me I may not be able to have surgery. Anyone else been through this?

Interested in more discussions like this? Go to the Gynecologic Cancers Support Group.

I have not, but I don't like all the Nos I would be getting another opinion

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@warrior2225 I understand the reason that your oncologist said that you cannot have radiation therapy or brachttherapy again. That's a treatment that only be done one time in the same location. My radiation oncologist told me that when I had radiation therapy for recurrent endometrial cancer.

Like @denisestlouie I'm unhappy about the "no's regarding chemotherapy. We aren't medical providers here on Mayo Clinic Connect so I cannot give you medical advice. I can share that if this were me I would be asking why the oncologist said "no" to chemotherapy and what are other treatment options are available. I would also be looking for another opinion from a different oncologist. Are you located near a comprehensive cancer center in the U.S.?

Find an NCI (National Cancer Institute) Designated Cancer Center:

-- https://www.cancer.gov/research/infrastructure/cancer-centers/find

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Why not more chemo? Not sure how many sessions you had but I've read of people having 25 or so. I just finished my 5th treatment on June 9th. I'm doing immunotherapy also and no radiation or anything else as of now. Not sure if she'll want that. I'm stage 3C endometrial cancer

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Get another opinion. I'm on another round of chemo treatment that is different from the first treatment I had almost a year ago. That one didn't work so well, as new tumors appeared and others increased in size. The treatment I'm on now has reduced the tumors and stopped new ones from forming. So, there are treatments out there for recurrence. The treatment I'm on now is a targeted drug that goes by the brand name ENHERTU. It's been effective for breast cancer and is now extended to treat endometrial cancer.

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Mine came back like you I couldn’t have more radiation so now I’m on immunotherapy drug. Feel ok since

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