Side effects from Keppra?

Posted by annabcd @annabcd, Mar 6, 2023

This is about my husband. He started having seizure like episodes four months ago once or twice a month that lasted 5-20 minutes. After trying to convince doctors these weren't anxiety attacks they did an EEG which was interrupted by a seizure like episode. They immediately got him on Keppra without confirming epilepsy and since then he's been completely out of it, has memory loss, slurs his speech, uneven pupils sometimes and others he smells something burning, cough, panic, sees flashing lights and colors,loses contact with the environment and more. He has stopped taking it since Saturday morning and he's much more conscious but still had episodes mostly with his head hurting, panic, burning smell and getting super sleepy when this happens. Memory is getting better.

Does anyone know if all of these are normal as far as bad side effects of keppra go and if so when they will go away?

Interested in more discussions like this? Go to the Epilepsy & Seizures Support Group.

Profile picture for dollynz @dollynz

Husband started on Levetiracetam (Keppra) 1 week ago after experiencing 2nd tonic-clonic seizure in 5 months. He's experiencing very poor mental health - is this your experience ? Does this go away after a few weeks of medication ???

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I have been taking that medication since 2019, and it causes osteoporosis issue.

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Profile picture for ysv12345 @ysv12345

I have been taking that medication since 2019, and it causes osteoporosis issue.

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Good Morning @ysv12345
Thank you for letting me know that. Happily, my calcium levels are OK, but I have only been on Keppra for just 6 months. I will keep an eye on that.
I remember from our conversation last year that you experienced some dizziness when reducing your Keppra dosage. How are you feeling now? Are you still dealing with any dizziness?
Chris

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Profile picture for dollynz @dollynz

Husband started on Levetiracetam (Keppra) 1 week ago after experiencing 2nd tonic-clonic seizure in 5 months. He's experiencing very poor mental health - is this your experience ? Does this go away after a few weeks of medication ???

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Doctor changed dose from 500 to 750mg; I am not dizzy any more

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Profile picture for dollynz @dollynz

Husband started on Levetiracetam (Keppra) 1 week ago after experiencing 2nd tonic-clonic seizure in 5 months. He's experiencing very poor mental health - is this your experience ? Does this go away after a few weeks of medication ???

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I have recently weened myself off of Keppra gradually. I had been taking it almost 2 yrs and had diarrhea everyday in the morning but when I was having joint health issues and there was some discussions on this board that keppra affected joint health also. Since being off it my joints seem to be improving! (great) Doctor wants to put me on Vimpat but I do not know yet whether I will start taking that.

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Profile picture for motobee @motobee

I take Keppra twice a day and so far no negative reactions.

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Yes, I take Keppra for grandmal seizures, I can only take 1 capsule per day. My system is really sensitive to medication, it works for me. I don’t have auras any more.

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Profile picture for motobee @motobee

I take Keppra twice a day and so far no negative reactions.

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Is anyone diabetic, with heart problems, what do you do naturally to lower your blood pressure?

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Profile picture for sissie7 @sissie7

Yes, I take Keppra for grandmal seizures, I can only take 1 capsule per day. My system is really sensitive to medication, it works for me. I don’t have auras any more.

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About a year ago, I was taking Keppra twice a day as is prescribed. Well, I decided to just start taking one pill per day and had a seizure. My doctor informed me that Keppra is a 12hr pill and you needed to take equal amounts twice a day. So what I did was cut down my total amount per day by cutting my pills in half. I would suggest you look into that so that you have some in your system for the entire day. God Bless

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Profile picture for hippele @hippele

About a year ago, I was taking Keppra twice a day as is prescribed. Well, I decided to just start taking one pill per day and had a seizure. My doctor informed me that Keppra is a 12hr pill and you needed to take equal amounts twice a day. So what I did was cut down my total amount per day by cutting my pills in half. I would suggest you look into that so that you have some in your system for the entire day. God Bless

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thank you for your information.. But why did you decide to lessen the dosage?? was it not agreeing with you?
I take it 2 times a day, and have no side effects... I wouldn't take less unless the doctor said it was OK. I am so afraid of having another seizure... good luck. I hope you stay ok.

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Profile picture for motobee @motobee

I take Keppra twice a day and so far no negative reactions.

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@sissie7 So glad to hear you and your doctor figured out what works for you!
I totally get the medication sensitivity thing - Keppra was rough for me at first, too. My doctor had me starting at 500 mg twice a day, which was way too much for my system. We've landed on just 125 mg in the morning and 150 mg at night using the liquid version. And honestly? It's been a game-changer! No seizures and the side effects are actually manageable now, thank goodness.
My doctor's been amazing through this whole process, really taking the time to adjust things bit by bit. He even told me that even though I'm 54, my body handles meds more like a kid would - which explains a lot!
What about you, what's your current dosage looking like? Are you on one of those extended-release versions where you only have to take it once a day? I've been curious about those!
Chris

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Profile picture for motobee @motobee

thank you for your information.. But why did you decide to lessen the dosage?? was it not agreeing with you?
I take it 2 times a day, and have no side effects... I wouldn't take less unless the doctor said it was OK. I am so afraid of having another seizure... good luck. I hope you stay ok.

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Keppra gave me diarrhea every morning but I was also having joint issues and after discussing here found out that Keppra can affect joint health. Not to say that I personally do not like any pills as "There is a poison in every pill". Sometimes we have no choice and have to take "pills" but if I have a choice, I believe the body itself is the greatest natural "healer". God Bless.....

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