Looking for causes for elevated liver enzymes

Are you taking any vitamin supplements? Many are implicated in high bilirubin and liver damage. Has anything changed about your diet or medications in the last two months.
Gallbladder would be my next guess.

Do not have a gallbladder. I do take a few vitamins. Should I stop everything?

I’m looking for advice on what testing should be done next. I just had an episode that started with severe right upper quadrant pain. I do not have a gallbladder and I don’t drink any alcohol. I’ve had this pain before but always subsided within an hour. This time it was over 12 hours till I was able to get relief at hospital. My alt was over 1600 and ast over 1100 and high ferritin level. Within one week they were back to normal with no medical intervention other then pain control. I still have pain but not as bad. I’ve had all sorts of testing done. So far mild fatty liver and positive Ana. I do have an autoimmune disease already. I’m waiting for a fibroscan to be done. Things that were mentioned were either lupus or autoimmune hepatitis. My doctors don’t have any clue other than something acute that happened to my liver. I am stressed out having no answers. Anyone have a similar situation and any testing that could be done to figure out my issue. I’m concerned if I continue to have these episodes it will do damage to my liver.

Welcome to Mayo Clinic Connect, @reppil63. Sorry to hear you are facing this health challenge. Makes sense you'd want to figure out these episodes.

Are the doctors going to do any treatment for the findings thus far, or are they waiting till all the testing is in? When will you have your fibroscan?

Thanks for the reply. So far no treatment. My fibroscan is this Friday. I’m waiting for a call back from my rheumatologist to see if he has any ideas. If I don’t get any answers I may ask for a referral to Mayo.

@reppil63 - I moved your posts here to this existing discussion where members are talking about high liver enzymes:

- Looking for causes for elevated liver enzymes https://connect.mayoclinic.org/discussion/looking-for-causes-for-elevated-liver-enzymes/

The reason I did this was so that you can connect with others talking about this topic, such as @caroljeans in this discussion and @dazlin @marjou @mayo99824 @neri47 @etnocaha @geedle12 @charicen @lexonpark and others who've talked about liver enzymes related to various conditions across the Mayo Clinic Connect community. Hoping they may offer some support and input as you go through testing, including a liver elastogropy (FibroScan) this week, and deal with severe right upper quadrant pain. They may have ideas as you try to figure out next appropriate testing to pinpoint the issues you are experiencing.

Have you by chance heard back from the rheumatologist, reppli63? If so, what did he say about your high liver enzymes and testing options to pursue?

Turns out autoimmune hepatitis stage 2.
Wish my doctors would have listened to me earlier.
Any one have this and had it reversed?

I have contacted my rheumatologist office 3 times. Explained my situation and so far have not heard a word back. I had a follow-up appointment already scheduled for August and they could only get me in end of July. Not sure if finding a new rheumatologist would help any. I still probably wouldn’t be seen till at least august. Depending on what the fibroscan shows I’m hoping my primary can help. No idea where to turn to next if he can’t help. He’s already said he has no clue

Can I ask if your liver enzymes were highly elevated? Mine were extremely high but they ended up back to normal within a week or so. No one seems to know the cause. It’s been about a month now and I have no answers. What were your symptoms of autoimmune hepatitis?

High liver enzymes is a sign of PSC. There are tests/procedures to determine if you have PSC. A competent GI doctor should be able to do the required tests.