← Return to Anyone take a Treatment Holiday? Intermittent use of ADT (hormone Tx)

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@glabelle

For those of you who have been on an initial round of ADT for 6, 12 or 18 months (or whatever time period), and have then taken a break, how long were you able to stay off ADT before your PSA rose to the point where you had to resume ADT? I am Stage IV oligometastatic and my oncologist wants me to take a break from ADT after six months. Have also been through SBRT. Thank you in advance!

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Replies to "For those of you who have been on an initial round of ADT for 6, 12..."

My husband has had vacations on and off for over 2 years. He started on a 6 month shot of Lupron along with Xtandi. He is now on Orgovyx and Xtandi. After 6 months his PSA was under 2.0 - he was off all drugs. Every 6 weeks he gets a blood draw - under 2,0 off meds until PSA goes over 2.0 then back on meds. So far so good.

When he is on a holiday, is he off ALL meds or just the ADT?

Most of the side effects you’re having are coming from Orgovyx. It reduces the testosterone to below 20 which causes numerous problems. These are the common problems.
Hot flashes
Fatigue
Muscle deterioration
Bone weakening
Brain fog
Depression
Weight gain
Difficulty in breathing

Nubeqa alone does not reduce testosterone, it reduces the ability of testosterone to work to feed the cancer. If enough time has gone by for your testosterone to come back after having used Orgovyx, then most of these side effects mentioned above do not continue to occur.