Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Posted by dougs72 @dougs72, Jun 22, 2024

Has anyone ever been on Duloxetine (Cymbalta) for nerve pain? I've had 2 doctors push this on me. I know that the side effects can be terrible and getting off of it difficult as it requires titration. One time I remember taking one pill, and not liking the way it made me feel, so not taking any more, and still feeling the "weirdness" from it 2-3 days later. and that was only 30 mg Please pass along any experience or advice from this medication?

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I take 30mg of Cymbalta and 300mg of Gabapentin in the morning, 300mg of Gabapentin at noon , 300 of Gabapentin at 5PM, and 30mg of Cymbalta with 300mg of Gabapentin at bedtime. I haven felt any pain in two years now. No side effects.

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I have been on duloxetine for about fours years. My pain doctor prescribed it because it can help with chronic low back pain. I also take pain medication. I have had no side effects and I believe it does help.

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@markl33

I have been on duloxetine for about fours years. My pain doctor prescribed it because it can help with chronic low back pain. I also take pain medication. I have had no side effects and I believe it does help.

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It's really not a good.med to be using. Do your Research

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Wow! I have been taking it at night for my 20 years now with no appreciable size effects, right, I’m 91.
Problem with medications is that side effects can be different for the takers, just something we have to accept.
My suggestion ask your doctor for a different medication . For sure in the day and age we all react differently and no need to suffer unnecessarily .
Hope this helps .

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@fef

Wow! I have been taking it at night for my 20 years now with no appreciable size effects, right, I’m 91.
Problem with medications is that side effects can be different for the takers, just something we have to accept.
My suggestion ask your doctor for a different medication . For sure in the day and age we all react differently and no need to suffer unnecessarily .
Hope this helps .

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@fef @poppawheelz @markl33 @jsiegel and others in this discussion, I don't want to sound like a broken record, but...
Every person is different.
Every body reacts differently to medication.
Every person has a different list of other medications that may interact.
Every person has a different list of other health issues or comorbidities.
Every medication, even OTC meds and some supplements have potential side effects.

So...please remember to say:
"I reacted this way to the medication, so you might want to be careful..." or
"Side effects include [nausea or ?] so be aware if it happens to you" or
"The prescription insert has the,following warning"
Dire warnings are scary...please avoid.

Many people, myself included, find duloxetine to be a blessing in managing our fibromyalgia or chronic pain. Others do not have such a positive experience.

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@sueinmn

@fef @poppawheelz @markl33 @jsiegel and others in this discussion, I don't want to sound like a broken record, but...
Every person is different.
Every body reacts differently to medication.
Every person has a different list of other medications that may interact.
Every person has a different list of other health issues or comorbidities.
Every medication, even OTC meds and some supplements have potential side effects.

So...please remember to say:
"I reacted this way to the medication, so you might want to be careful..." or
"Side effects include [nausea or ?] so be aware if it happens to you" or
"The prescription insert has the,following warning"
Dire warnings are scary...please avoid.

Many people, myself included, find duloxetine to be a blessing in managing our fibromyalgia or chronic pain. Others do not have such a positive experience.

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I appreciate your response, but I also assume that all the possible scenarios would have already been discussed with the prescribing doctor and that the user would have the common sense to read the instructions for a list of side effects. I can only report as to how I reacted to any given medication or combination of medications and really don’t feel I need to go over all the obvious due diligence the patient needs to have done. Surely just my opinion though.

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My Dr. now has me on 60mg of Cymbalta and 1200mg of Gabapentin and that helps me even more. I’m trying to get down to 600mg of Gabapentin. It’s a work in progress and I’m feeling a bit like a guinea pig but I can’t argue with success. Of course everyone reacts differently.

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I have been on Cymbalta 120mg for year’s now. Probably since 2008. It was given to me for depression and nerve pain. I really don’t think it bothers me to much, but I’ve been on it so long, who knows? I have a lot of permanent nerve issue’s from my original injury back in 2000. And 25 years later, and 16 spine surgeries, 2 SCS, a Morphine Pump that got infected and almost killed me, and I’m still in a lot of pain!! So I’m sorry I’m no help, but all of the medicines I’ve been on have not helped. Hang in there!

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@patrickf1

I take 30mg of Cymbalta and 300mg of Gabapentin in the morning, 300mg of Gabapentin at noon , 300 of Gabapentin at 5PM, and 30mg of Cymbalta with 300mg of Gabapentin at bedtime. I haven felt any pain in two years now. No side effects.

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What kind of pain did you have?

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I've been taking duloxetine to treat my depression for almost 10 years, along with nortriptyline.

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