My TRIMIX experience

Posted by maverick75 @maverick75, Jan 4 9:27am

I've been using Trimix for about six months with outstanding results. It did take some experimentation to figure out the best way to make it work for me. With hopes that it may help others, here's what I discovered using this medication: (BTW, I'm 71, one year post SBRT and 4 months Orgovyx)
- I have had to use the oral antidote several times (works well) in the early dose experimentation days for super hard erections lasting more than three hours (4tablets of 30 mg pseudoephedrine. Don't make the mistake of buying the extended release pseudoephedrine tabs). Make sure you have this on hand before you start this medication!
- I had to find the sweet spot for the injection site and depth. For me turns out to be the 10 and 2 o'clock position with the 1/2" needle almost fully inserted around mid-shaft.
- Shelf life on the Trimix in the refrigerator is limited. I can definitely see a difference in the results at the 3-4 week period. For me, it became pretty useless after 4 weeks, even at a higher dose. To help extend the life, I now fill all syringes with the needed dose as soon as I get the medication and immediately place all syringes into the freezer until needed. Now, I take a syringe out about 30 min before needed and it's ready to go. This is working well and my pharmacist said this should extend the shelf-life to 6 months or more.
- After injecting, massage the entire penis and base to help distribute the medication throughout the muscle structure. This will help significantly.
- Stand for the first 5-10 minutes after injection as gravity aids in the blood flow into the penis.
This medication has been a lifesaver for me. I was afraid I'd never see a useful erection again. Now, I'm back to 18 in that regard-- actually better than 18 as my erection stays hard even after an orgasm! Best of luck guys! Be aware that your partner may hide your medication if you use it to often. (-:

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

@graybeard46
I was told not to use pills & trimix and read it many different places also.
Jake

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Probably no right or wrong. Probably depends on the dose of Trimix and how sensitive you are to the medication. If your erection on Trimix alone is > 3 hours, probably best not to mix oral with injectable. It's never been an issue with me even at higher doses of Trimix.

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@retireddoc
Good afternoon,
Could you explain what the concern is in using both. Some doctors are adamant about using one of the other but not both.
What is the purpose of taking a pill that cause an erection?
Thank you,
Jake

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I’m having a tough time again with my Trimix third attempt yesterday at .15 dose half erection but painful stinging the whole time making me want to give up trying sadly

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@jakedduck1

@retireddoc
Good afternoon,
Could you explain what the concern is in using both. Some doctors are adamant about using one of the other but not both.
What is the purpose of taking a pill that cause an erection?
Thank you,
Jake

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If you have an erection that last more than 4 hours or so it can damage the penile tissue. If a man has an erection than lasts more than 4 hours it is advised to go to an ER so they can intervene. From what I have read, men that mix taking oral medication like Viagra with Trimix run the risk of having a prolonged erection (called priapism in medical terms).

I am not sure what you mean by your last question. Men that have erectile dysfunction (can't get an erection) sometimes take oral medication (like Viagra) to help them get hard.

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@graybeard46

I’m having a tough time again with my Trimix third attempt yesterday at .15 dose half erection but painful stinging the whole time making me want to give up trying sadly

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Graybeard for me when I started the injections it was uncomfortable throbbing for a period of time, each time but as my penis got use to the stretching,(had been a long time of not good errections) it got to be a shorter and shorter time of discomfort. Now @ 100 injections in, aside from initial injections no more discomfort. It is uncomfortable afterwards even now but just sitting in recliner for @ a hour or so, takes discomfort away. Not sure if other have same experience but this is mine and have absolutely no desire to go without the use of the Trimix. So worth it to me. Hope this helps

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@graybeard46

I’m having a tough time again with my Trimix third attempt yesterday at .15 dose half erection but painful stinging the whole time making me want to give up trying sadly

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When I was new to Trimix, I found I had that stinging when I injected it in the wrong area. In my case, it was too deep. I found for me, I have to insert the needle at the 10 or 2 o'clock position and insert the length of the needle but just until the syringe reaches the skin (no depression of the skin). After having done it so many times now, I can feel the slight resistance when the needle penetrates the erectile tissue. After the injection, make sure you massage your penis and the base area to distribute the medication and stand while you are doing this and for the next 5-10 min. Don't give up.

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@graybeard46

I’m having a tough time again with my Trimix third attempt yesterday at .15 dose half erection but painful stinging the whole time making me want to give up trying sadly

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My initial attempts with Trimix were marked by an achiness that lasted for two or more hours. Because I wasn’t getting the firmness I desired, my urologist increased the strength of the dose (went from #8 to #9 as offered by menMD). That resulted in even more discomfort to the point I stopped using that particular formulation. I learned that about 20% of men suffer from this discomfort which is caused by the aprostadil component of Trimix. MenMD offers low-aprostadil versions which is what I am currently using (#6). The discomfort, though still present, is at a much lower level and more easily tolerated. Another option is Bimix that contains NO aprostadil.

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@jakedduck1

@vancouverislandhiker
You may not have injected it correctly. That recently happened to me. I thought the medicine needed reformulated so I went back and had the doctor inject the same dose and thought I wasn't injecting it coyand he was right. When he injected it all was fine. You might want to try that or try the versions that goes in the urethra or the topically applied one. I understand the last two don't work quite as well as the injections but might be worth a try.
Take care,
Jake

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@vancouverislandhiker, does your reply have a mistype ("coyand"??)? What do you mean by that? Thank you for your comments.

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@jasonfarmer

Graybeard for me when I started the injections it was uncomfortable throbbing for a period of time, each time but as my penis got use to the stretching,(had been a long time of not good errections) it got to be a shorter and shorter time of discomfort. Now @ 100 injections in, aside from initial injections no more discomfort. It is uncomfortable afterwards even now but just sitting in recliner for @ a hour or so, takes discomfort away. Not sure if other have same experience but this is mine and have absolutely no desire to go without the use of the Trimix. So worth it to me. Hope this helps

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Thanks Jason , you gave me hope, I have used a pump off and on for last 2 months but not often enough , pump never worked but your point of stretch the sleeping giant makes sense , I’ll try to be patient but by end of year if not satisfactory will try implant , thanks again for your reply

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