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PROMISE Study: Registry of PCa Genetics and Outcomes

Prostate Cancer | Last Active: 15 hours ago | Replies (25)

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@pdcar4756

I had my genetic counselor phone call yesterday. It went very well and was very informative. I had no genetic mutations related to prostate cancer for the group of genes that COLOR looks at. The counselor told me there is one gene they do not look at at this time (HOXB13) that is of growing interest as it relates to prostate cancer. I also learned that there are other genetic tests for cardiac disease and how the body breaks down and handles medications. COLOR, I assume has a website which I've not yet visited to see what else they offer in the way of genetic testing (of course these other tests won't likely be free). I also learned that COLOR and Promise work in partnership but are separate entities. Promise is the prostate cancer study. COLOR is the lab that does their genetic testing.

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Replies to "I had my genetic counselor phone call yesterday. It went very well and was very informative...."

I was real surprised when Promise sent me a map that shows where in the world my family came from, with the percentages of each country mostly broken down.

Took them at least a year before they sent the map, but it was real good information to have.

Hi @pdcar4756 Thanks for sharing some of the information from your call with the genetic counselor! Below is a link to a 2022 publication reporting results from ongoing research (hopefully if funding is still intact) on HOXB13 as it pertains to prostate cancer and potential therapies.
https://news.feinberg.northwestern.edu/2022/05/10/new-regulator-of-prostate-cancer-metastasis-discovered/#:~:text=HOXB13%20is%20a%20prostate%2Dspecific,are%20the%20mainstay%20of%20care.
Bill