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My Gleason score is 7 - 3+4. How long can I live without treatment?

Posted by mayoclinicadvice23 @mayoclinicadvice23, Jun 11, 2023

My Gleason score is 7 - 3+4,. How long can I live without treatment? Since I decided not to get any treatment, because of horrible side effects, I was wondering, if someone who experienced the same condition, will share his experience with me.

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ezupcic | @ezupcic | 2 days ago
In reply to @tdgillett "I'm 79 with 3+4 Gleason (and a 3+3) but only 2 out of 12 biopsy samples..." + (show)
@tdgillett

I'm 79 with 3+4 Gleason (and a 3+3) but only 2 out of 12 biopsy samples showing cancers. PSA was 7.67 October 2024 but was 4.6 in May 2025. Active surveillance for now, but the latest PSA was a (pleasant) surprise. Scheduled for another MRI and biopsy in early 2026. Anyone else have PSA declines for no apparent reason?

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I’m 61. PSA was 8.1, then 7.8 two days later than two months later 5.4 in March. Did you check your Free PSA? My MRI was PIRADS 3 with no focal lesions. Doing another PSA in June and probably another MRI if numbers go back up. Maybe a benign issue. If numbers go way up and MRI notices a change then probably biopsy.

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dougincali | @dougincali | 1 day ago

I had the same numbers. When my prostate was removed the cancer was not contained in the prostate.

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Jerry | @jerryegge | 1 day ago
In reply to @dougincali "I had the same numbers. When my prostate was removed the cancer was not contained in..." + (show)
@dougincali

I had the same numbers. When my prostate was removed the cancer was not contained in the prostate.

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What did the MRI show before your prostate was removed?

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ppettis | @ppettis | 1 day ago

I have the same question. My Gleason is 3+4, and I am seriously considering observation vs. treatment. I am 70, and if I can live another 10+ years without treatment, that may be a valid option for me.
Any firsthand experience would be appreciated.

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rtyrrell | @rtyrrell | 1 hour ago

Hi. I’ve been treating mine for 16 years starting at age 56. Now 72. Everything has side effects but I felt I can deal with it. Easier than the cancer growing and spreading.

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