Reclast - Please share your positive experiences

I agree with Victor.

This paper shows that half dose is as effective as full dose and lasts a year. That can be monitored with CTX analysis to determine when the next infusion would be warranted.

Oh dear I feel so uncomfortable with all the possible side effect with Reclast
Thank you so much sharing!

Thanks for the link, @normahorn. I hope those who are considering a lower dose of reclast bring a copy of the pdf to their doctor's appointments. If successful in getting a low dose reclast, please share CTX changes and therapy outcome.

For those who are going to use reclast after prolia cessation, a low dose reclast might need extra monitoring as the timing and magnitude of CTX increase will be unpredictable.

It may be early to know if the lower dose will provide lasting bone density. This paper states that while there was an increase in bone density on the lower dose it is unknown whether it will have lasting effect. It would be awesome if it does! The study was only for one year, though.

I think the current belief is that the higher dose, maybe even given in multiple lower dose sessions, is what is needed to give the 3-5 year (minimum) benefit. I don’t know if my insurance will pay for multiple lower doses because it is charged as a hospital visit - which is always incredibly expensive. Even if the infusion is given at a clinic or infusion center, those facilities usually bill like a hospital visit- something to do with the quality of care/facility that qualifies them as a “hospital”.

I’m going to ask my endocrinologist before this upcoming infusion. I did ask the cancer enter rheumatologist (who is co-provider for my bone issues) about delaying the third infusion and he stated that it needs to be given three years in a row.

I agree with Victor.

This paper shows that half dose is as effective as full dose and lasts a year. That can be monitored with CTX analysis to determine when the next infusion would be warranted.

I had a Reclast Infusion 4/1/25 and I have been feeling poorly since and today is 4/13. I got the pain in the left eyeball and thought m head was going to explode the day after infusion. I too saw eye doc and he did not see that I needed steroid drops. The pain finally subsided but it went to back of neck & shoulder . Then it went from there after 3 days into my right jaw where I had teeth removed (I was on Prolia and used oral surgeon one year before). It has subsided after 3 days. I’m better today but still feel crummy. Pain has subsided🤞I am a long term chronic pain patient on pain meds as well. I will tell you I had to use six Tylenol 500 mg each for two days and least two 500 mg since the infusion with normal pain meds. This morning I woke up headache free and yesterday. I’m hoping I can do a little housework starting tomorrow. This will be 12 days in bed mostly for me. I suffered agonizing bone pain with Prolia (4 shots over 2 yrs. Pain started last year so I refused to take. Due to fracture risk they put me on this and I’m reluctant to do it again) Prolia about killed me last year. I couldn’t bend over to pick something off floor and woke up in morning not knowing if I could get up in so much pain. I really thought I was going to die (it was so bad). I couldn’t walk. I missed Christmas and New Years with family. Too much pain. I am hoping to feel better, but I can’t hold my breath. I’ll update in a few days. These drugs are powerful and I wish I had never heard of them. Now I’m stuck because I have spondylitis, severe scoliosis and no space disk in back. Oh and I want to mention my hands hurt so bad I couldn’t cook for several days. It’s been hell for me. Think twice before you do these drugs. It’s a lifetime you have to continue.