How to stop Mirtazapine? I am on 15mg a day

Posted by Afridi @afridi, 6 days ago

I have been in depression since January 2021 or earlier but started taking medicines since March 29 2025

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I was taking Mirtazapine for about 3 months and I didn’t feel well from the medication. I couldn’t get in touch with the doctor to see what he suggested I do, long story short, I simply weaned myself by slowly reducing a day each week and I finally got off of them. I don’t recommend that you do this but I felt fine with my own method, you can also ask the pharmacy but they will probably tell you to contact your doctor. I would like to add that this drug had more side effects than benefits for me but I have also read stories that people found it very helpful.

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@afridi
Since you haven’t been on it long, let your doctor know you want to stop it. I could not take mirtazapine because it made me so hungry and I do not want to gain more weight. They tried different medications and combinations that didn’t work for me for over a year. I finally landed on a combination of Sertraline and Bupropion that works some for my major depression.

What other medications have you tried?

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@dlydailyhope

@afridi
Since you haven’t been on it long, let your doctor know you want to stop it. I could not take mirtazapine because it made me so hungry and I do not want to gain more weight. They tried different medications and combinations that didn’t work for me for over a year. I finally landed on a combination of Sertraline and Bupropion that works some for my major depression.

What other medications have you tried?

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I hear you! I have been taking Mirtazapine for almost 20 years. I just have had enough. I gained so much weight, can't enjoy the foods I like because I am always worried about weight.
I will say it helped for a time. But then I think it just became a habit. I've been cutting pills for awhile and am now down to 1.75 mg. Soon to be off completely.
I think in retrospect that these drugs have their place. I just think we take them for too long.
Hope you can get through this time without too much trouble.

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