Palmitoylethanolamide (PEA): Anyone had success?

Posted by wisfloj @wisfloj, Jan 26, 2020

Palmitoylethanolamide (PEA) user for at least 6 months. Seemed to work after several weeks, then not, then somewhat, now not at all and the burning pain is spreading to most of my body. Anybody find success? Is this how it works for you as well? Just hate to throw away money and continue unnecessary/ ineffective supplements. I use the Ergomax brand.
Thank you fellow sufferers! Appreciate this forum and people willing to share, advise and encourage!

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Profile picture for jchet @jchet

Be Careful. I ordered PEA from Amazon, but will return it as I found out that you should not take it if you’re on Eliquis (blood thinner).

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I’ve been taking it with Eliquis for several months. No problems.

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Profile picture for margitdill @margitdill

I’ve been taking it with Eliquis for several months. No problems.

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I would suggest you ask your doctor. I don't know if you've cut yourself or have seen that your clotting okay but if you're in a car wreck and you're cut up bad you could bleed to death if that's what The warning is....

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Profile picture for jchet @jchet

Be Careful. I ordered PEA from Amazon, but will return it as I found out that you should not take it if you’re on Eliquis (blood thinner).

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Where did you read about PEA and eliquis?I am on eliquis but wanted to give PEA a try.

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Is PEA safe to take with low dose aspirin therapy?

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Profile picture for stellarg @stellarg

I tried the first 300 mg dose last evening but was awakened about 6 hrs. later with severe itching on both lower legs and ankle areas...I don't know if cause/effect applies. Has anyone else experienced similar PEA side effect?

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In Italy, neuropathy is treated with Lipoic Acid & PEA. Has anyone tried PEA or the above combination in the USA?
Jim in SC

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Profile picture for jeaiken @jeaiken

In Italy, neuropathy is treated with Lipoic Acid & PEA. Has anyone tried PEA or the above combination in the USA?
Jim in SC

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@jeaiken what is PEA

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Profile picture for jeaiken @jeaiken

In Italy, neuropathy is treated with Lipoic Acid & PEA. Has anyone tried PEA or the above combination in the USA?
Jim in SC

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Hi Jim @jeaiken, We merged your post with an existing discussion so that you could meet other members who have mentioned using Palmitoylethanolamide (PEA) for pain. If you click the link below it will take you to the beginning of the discussion where you can learn what others have shared.
-- PEA for pain relief?: https://connect.mayoclinic.org/discussion/pea-for-pain-relief/

@1kay2 and Jim, Here is some additional information on PEA that might be helpful:
-- Palmitoylethanolamide (Pea) - Uses, Side Effects, and More:
https://www.webmd.com/vitamins/ai/ingredientmono-1596/palmitoylethanolamide-pea

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Profile picture for jeaiken @jeaiken

In Italy, neuropathy is treated with Lipoic Acid & PEA. Has anyone tried PEA or the above combination in the USA?
Jim in SC

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@jeaiken
I have no noticeable short term effect from R-ALA and PEA. Possibly slight effect longer term (over 3 wks+). I think it is good to mention dosages when discussing any treatments (since YMMV), so, R-ALA 100-300mg/day and PEA 300-1200mg/day.

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Profile picture for 1kay2 @1kay2

@1kay2: Palmitoylethanolamide (PEA) is an endogenous fatty acid amide that is naturally produced in the body and found in certain foods like egg yolks and peanuts. It has anti-inflammatory and analgesic properties, making it a potential treatment for various pain conditions, including neuropathy.
REQUEST TO ALL: PLEASE DON'T USE ACRONYMS WITHOUT FULL NAME OR EXPLANATION OF WHAT THEY STAND FOR. THANKS!

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Profile picture for stellarg @stellarg

I tried the first 300 mg dose last evening but was awakened about 6 hrs. later with severe itching on both lower legs and ankle areas...I don't know if cause/effect applies. Has anyone else experienced similar PEA side effect?

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Please share your experiences using PEA for post surgical nerve pain or neuropathy.

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