Post viral syndrome peripheral nerve hyperexcitability
Hi everyone,
I’m a 36-year-old navigating recovery from what’s been described as post-viral small fiber involvement and motor nerve hyperexcitability.
How It Began:
It started after a viral illness in August 2024, during a time when my whole family had upper respiratory symptoms.
I developed fever, diffuse headache, and left-sided temple pain, which later localized and became persistent.
By January 2025, I began to experience:
Burning sensations
Pins and needles
Odd wet or sunburn-like skin feelings
Muscle fasciculations (twitches) across my body
Migratory muscle pain and intermittent joint discomfort
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Workup So Far:
MRI of brain and cervical spine: Normal
Autoimmune workup: Negative
Skin biopsy: Normal epidermal nerve fiber density
Nerve conduction studies & EMG (lower extremities): Normal
CBC, CMP, CRP, ESR, CK, aldolase, B12: All normal
No evidence of large fiber neuropathy or motor neuron disease
No clinical weakness or atrophy
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Current Working Diagnosis:
Post-viral small fiber sensitization
Motor nerve hyperexcitability (likely benign fasciculation syndrome or similar)
Significant health anxiety, especially due to my medical background and profession
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What’s Helping Me:
Gabapentin (600 mg at night)
Supplements:
Magnesium glycinate
CoQ10
Alpha-lipoic acid (ALA)
Omega-3
Curcumin
B-complex
Vitamin D3 + K2
Ashwagandha, glycine, apigenin (for calming and sleep)
Exercise: Strength remains intact and working out reinforces my confidence
Mind-body tools:
Headspace and Curable app
Weekly visits with a psychologist
Gratitude journaling
Somatic calming techniques (breathing, grounding, mantra work)
New mantra I use daily:
> “One in a million. I am strong. This will pass.”
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Biggest Lessons:
Even with scary symptoms like widespread twitching or burning, the body can be in a state of hyperawareness, not disease.
I’ve learned the importance of regulating fear and stress to support nervous system healing.
Benign doesn’t mean painless—but it does mean hopeful.
Working with a neurologist, psychologist, and staying grounded in scientific reasoning has helped me reclaim my peace.
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Happy to connect with anyone navigating something similar. You're not alone—and your body is capable of calming, rewiring, and healing.
Interested in more discussions like this? Go to the Neuropathy Support Group.
No concrete time table. He said months to years... I'm mentally preparing for this is just my new norm. As long as things don't progress I am happy I am complete function and can sleep at night with the help of medication.
Hi Josh,
I know this is a bit of an old post but I found it today and it feels like I could have written it myself. I am having so many unusual sensations after an unknown illness and I keep being told it’s likely just anxiety. It’s getting better and better slowly, though. How are you doing? Any improvements?
O am going through similar things and really struggling
I have had exactly the same even symptoms, even down to what your blood work was and supplements, although I take a couple more, I am a nutritionist. I’ve been to the neuro worst day of my life, same tests as you and spiralled into anxiety and despair. Very hard to climb out of the hole when you get there. I had significant stress before I started noticing the twitching with a bout of Covid preceding it. The whole thing has been hideous but trying to keep moving forward !!
Just saw your post. I posted upthread in April about my progress. I’m happy to say I’ve continued to improve in most ways, though still have some issues. Overall, I’m ecstatic to be doing so well. Glad to see you moving forward. I certainly hope you and others have improvement too.
Thank you so much that gives me hope .. some symptoms have improved although I’m not sure how much was also masked by chronic stress.
Hi Gabi about the same. Still bodywide twitches, for the past 2 months I have had this stiffness in my right glute and calf. Not sure what to think of it seems to be pretty common the BFS reddit. I just hit my 6 months mark of fasciculations without any significant weakness so I take that as a win. God bless