How are you doing with the MF? Any change in treatment protocols? I have ET-CALR x 17 years, HU x 6 years. I understand CALR makes me somewhat more likely to develop MF, tho there seem to be genetic variables within CALR mutations that are still not well understood. But my hemo explained that anybody with ET will progress if they live long enough. Thanks for sharing your experiences. It's helpful to know how these things play out for others over decades. So many on here are very newly diagnosed, dealing with that initial shock, and cannot (yet) identify with us long-termers.