Now that this discussion has revived, look at this analysis from the NIH of several B6 studies.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8483950/
The issue is a lot more complicated than was earlier thought, and it appears that when we think our body is producing too much Vitamin B6, it may in reality not be synthesizing/releasing it efficiently. So even without excessive B6 from supplements or fortified foods, one can have a high serum level.

It is still unclear what percentage of neuropathy cases may be caused or exacerbated by high levels of vitamin B6

I haven't studied the Coburn site and report, but since B6 is water soluble, the hydration approach is probably on the right track, and adding exercise to our daily routine is pretty much always a healthy suggestion...

Just know that any claims of other supplements or medications to reduce B6 have not been studied.

Has anyone tried the RDAB^ Protocol? What was your experience?>