Prolia discontinuation
Hi, due to an osteoporosis diagnosis, I took two injections of Prolia six months apart and due two side effects, I want to come off of it. I do not want to transition to a bisphosphonate or remain on one. How do I take myself off of Prolia safely? I am not getting a straight answer from my doctor.
Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.
I am in your exact situation. What did you decide?
Who was the very good endocrinologist in Orlando and where did they move to?
It was about 5 years ago and I looked for endo for troubles with my thyroid by internet, I do not remember.
Now I looked for endo anywhere in the USA for osteoporosis.
Having been on Prolia for 4 years, I needed 2 teeth extracted. I had an excellent oral surgeon who had a lot to say about Prolia and other osteoporosis drugs. I got the impression I may not have needed to go off Prolia for this. Zometa (which I was planning on using to transition off Prolia) horrified him. For the real expert opinion, I think it is the oral surgeon you need to discuss this with.
237 women who were on Prolia, SUSPECTED drug (only ones who have reported this adverse effect to the Government) in Australia have osteonecrosis. This is the death of the jaw bone (ONJ). It can occur when you have invasive dental work when you are on Prolia.
The trouble is there is no data. Drs and endocrinologist, l think are flying blind. So no studies on which bisphophonate is most effective, how long one has to be on the bisphophonate, or as you mention exactly how many years that we have been on Prolia?? Like you l have asked drs if they have patients who have successfully transitioned and no definite answer.
I agree with you who said why is it still on the market. Here in Australia, l have read AMGEN now have 76% of the market as it seems to have become the Dr's choice. All very distressing for those of us trying to get off it.
I am on prolia I have 3 injections in the last 18 months and I would like to come off it due to side effects can I do this savely by going cold turkey
It is my understanding that without a followup drug like reclast you would be at risk of rebound.
brunobozo, you can't stop Prolia without the risk of multiple fractures, unless you take something to counteract rebound, Prolia stops acid producing cells osteoclasts in their final stage. But those cells collect sometimes combining to form large aggressive cells. When you quit Prolia these cells are released. Some experience what are called cascade fractures where one vertebra collapses after another. It is even dangerous to be late for a Prolia injection.
The usual drug to follow Prolia is Reclast because it is the strongest bisphosphonate, the most capable of blunting those osteoblasts.
I do think it is good that you are stopping Prolia, but hope that you don't try it without a replacement medication
I have only had 1 Prolia injection and won’t be having any more
Walking twice a day
Joined the gym
Upped D3 and added K2
Feeling good
Hopefully that’s enough
I had no symptoms just the result of Bone Density