Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Posted by dougs72 @dougs72, Jun 22, 2024

Has anyone ever been on Duloxetine (Cymbalta) for nerve pain? I've had 2 doctors push this on me. I know that the side effects can be terrible and getting off of it difficult as it requires titration. One time I remember taking one pill, and not liking the way it made me feel, so not taking any more, and still feeling the "weirdness" from it 2-3 days later. and that was only 30 mg Please pass along any experience or advice from this medication?

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It worked so good…I’m guess I’m just a light sleeper. My sister has taken it for a long time, increased amount, and she has no issues.
I wouldn’t worry…enjoy the comfort!

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@ch47

It worked so good…I’m guess I’m just a light sleeper. My sister has taken it for a long time, increased amount, and she has no issues.
I wouldn’t worry…enjoy the comfort!

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I take Horizant, a time release gabapentin, with regular 100 gabapentin as fill in, up to 3 times a day.
I can make it through the night now.

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@cameo2025

Just wanted to add that they also push Gabapentin on spinal stenosis patients. Off-label drugs used for their side effects is wrong and not effective. I find it ridiculus that doctors do this, many have suffered terribly trying to stop these drugs. I'm a spinal stenosis, chronic pain patient, opposed to the surgery I was offered. A laminectomy with medial facetomy. Suffereing now over 2 years. I wish people would do their homework on these off-label drugs and any drugs for that matter--

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Getting off gabapentin and starting Lyrica. Had a Laminectomy and the pain is now across my back where I use to have it just on the left. The surgeon was an idiot. He did not do what he said he was going to do, laminectomy at L3 and L4. Just did L3 so the space in spinal canal is still very narrow. Also was suppose to do a disectomy and didn't do it. Also have neuropathy in both legs also which is new. I was doing better before surgery.

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I’ve been on Cymbalta and Lyrica for awhile now. It doesn’t take away my pain completely but does help some. There have been a few times when I ran out and after about 3 days the withdrawal symptoms came on and yes they were bad. I have tapered down in dose in the last 2 months and have been fine. Went from 60mg down to 40mg. The Lyrica I take different amounts off and on depending on how I’m feeling. I started with low back pain which has been resolved but now am dealing with nerve pain from my neck that is affecting my arm. It’s been 3 months now that this has been going on. Appointment with neurosurgeon in about 10 days to find out what the issue is. I just want to feel normal again.

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I’ve been skimming through all your comments. I was first diagnosed with TN, September 2014. I just came home from vacation and thought it was related to a dental issue.. The pain became so severe as I waited to see if the dentist because it was a holiday weekend. I went into the Dennis, crying explaining the symptoms he tapped on all my teeth. I had no pain. Danny told me you need to go see a neurologist, I think you have tic de la rue. Otherwise known as trigeminal neuralgia, my dentist diagnosed me between September and December. I was on so many medication‘s to help relieve the pain. Nothing worked very long I just wanted to die. The pain felt like I was being electrocuted in the electric chair. It dropped me to my knees, and I swear I have PTSD from it. I couldn’t continue and all the meds I was taking. so I had to find something else to help me. I found a great surgeon at UCLA had MVD.
Sx, it was the scariest thing I’ve ever done. I had no choice. Long story short 10 years later and I’m still battling this evil MF. And it’s evil I am on duloxetine, pregabalin and Baclofen. I have pain every day since January 2 and now it’s March 24 even while taking all these meds. I did acupuncture for six months didn’t really help in my opinion. And now after talking it over with my neurologist, I’m gonna try Botox. And if that doesn’t work and the pain comes back where it’s 100/10 and excruciating and drops me to my knees I’m gonna cut the damn nerve. I appreciate you listening, normally, I just talk to my animals.

So what I’d like to do has anyone ever tried Botox for TN?
I am constantly searching for something new, in 10 years later, I find stuff. The facial pain association in Florida has been very helpful. And I think the mayo clinic for being another avenue for me to find help or talk to anybody and get their opinion
Again, thanks for listening
MaryB60

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Hi. I also have TN and go through that excruciating pain every winter. I didn’t have MVD or Botox. I’m going to see a Pain Anesthesia Specialist. He’s supposed to be great so I’m waiting months before seeing him. It takes that long to get an appointment from him.
I hope this gives you another option. I wish you well. Take care.

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I've been on Duloxetine, 60 mg, for a few years. At first I noticed it made noticeable difference in my morning pain. Made it easier to get out of bed. Now, not so much. I've talked to my PC about upping the dose or changing meds but she says no because of my mild chronic kidney disease.

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I should say I have terrible Fibromyalgia from head to foot and severe spinal arthritis.

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@celia16

That is one of my older post when I had intermittent burning on various places on my body. It would appear sporadically on my arms, legs and feet. Never all at once. It usually lasted about a couple of hours or all day. It felt like a sunburn. It came about suddenly when I started taking mega doses of Vitamin B12 per my doctor’s instruction to treat my deficiency. It lasted a couple of months, before it subsided. Then it stopped and I don’t get it anymore.

I do still a quarter size spot on my right foot that will intermittently burn in waves. It’s different from the sunburn like sensation I got as described above. It usually does it for 1-2 minutes and stops. It’s not bothersome enough to take meds for. Hope that helps.

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Hi my burning started out on my face and then after my pump was replaced the pump and the tubing in the back shortly after that I started getting burning all on my upper body the back of my arms were the worst but it's horrible it's right when I sit down and laid back it gets after about 15 minutes it's really really bad I had to go to the hospital when I stayed in 4 days and they couldn't figure out what was wrong. I'm kind of thinking it might be where the tubing is in my spine could be pressing on a nerve I'm sure the doctors will say oh no that can't be it

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@gloriape

I've been on Duloxetine, 60 mg, for a few years. At first I noticed it made noticeable difference in my morning pain. Made it easier to get out of bed. Now, not so much. I've talked to my PC about upping the dose or changing meds but she says no because of my mild chronic kidney disease.

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Taken Cymbalta for years for pain. Really makes a difference

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