Tips on minimizing withdrawal symptoms from Effexor (aka Venlafaxine)
I have been taking Effexor/Venlafaxine for years and tried to get off it a few times but each time I try to give up the chemical withdrawal symptoms are a horror story and I give up giving up. Anyone got any tips or tried and tested strategies? Thank you
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Additional info to my post: First I’ve been tapering slowly and went down to 37.5mg without any symptoms. Then I went to 0 and got a mental breakdown. Then my doc prescribed me 60mg of Cymbalta and I’ve switched the drug (quit Ven). Have been taking Cymbalta for 20 days, 0 improvements whatsoever. So yes basically I’ve understood that if I continue I’ll just get further and further physically hooked on Cymbalta without getting any actual help from it. That’s why I went cold turkey. I didn’t want to feed my body with it, not another milligram, so my cells are less likely to develop dependence.
Oh wait. From which medicine am I experiencing withdrawal syndromes then. Venlafaxine? Cymbalta? I feel like SNRI in general. My body need to get used to not having any dose of SNRI. How? No clue. My doc seem to have no clue as well.
Hi, @chicago1211 - welcome to Mayo Clinic Connect. Discontinuing some antidepressants and anti-anxiety medications can be like going through hell, so to speak, and make you feel just awful. I had one withdrawal from an antidepressant that was evidently too fast, and I finally had to sit myself in the corner of my kitchen on the floor to make sure I didn't say or do anything I didn't want to be doing and asked my husband to please take me to urgent care immediately. They had to give me an antianxiety medication to take over the weekend to smooth out my taper and the side effects I was experiencing.
I don't know how serious you are about saying you want to kill yourself, but I do want you to meet @jimhd, who may have some thoughts to share with you. I also want you to know that this is a safe place to talk, even about tough stuff that can happen during a taper. Others who may identify with what you are experiencing right now and be able to provide some support include @brightwings @sandij @laujenkins @cp6401.
chicago1211, if at any point you start to feel like you may consider hurting yourself, please call or text the 988 Suicide & Crisis Lifeline https://988lifeline.org for immediate help. Your safety is the most important thing to us.
Have you chatted with your doctor about your move off of this medication and how things are going? If so, what did she or he say?
I completely agree with @texasduchess! I believe you’d be better tapering, the yo-yo ing is so much for your body to handle and quite frankly, I don’t understand how someone can be successful doing every other day. It’s been a week an a half of my off Venlafaxine completely and I’m starting to feel great! I did it by tapering and yes, it was tough, but I feel like it was much more manageable than every other day. Again, I am NOT a doctor, but felt this was the best way for me to go about it!
Good luck! We are here for you! 💜
Tell your doctor that you feel like you're going through hell and want to kill yourself. Read why and how better to get off Effexor here--https://www.nytimes.com/2019/03/05/health/depression-withdrawal-drugs.html.
Yes, your "cells are craving" the Effexor--antidepressants are VERY powerful; Effexor affects your brain's neurotransmitters–serotonin and norepinephrine. While reducing, or after getting off Effexor, it takes your brain a while to figure out how to rebalance serotonin and norepinephrine.
OTC medications and supplements can help with some of the withdrawal symptoms. Ben*dryl, Bon*ine, or other seasickness remedies can reduce/minimize the dizziness/vertigo. Here's a good article re how to mitigate withdrawal effects with supplements--https://www.4mind4life.com/effexor-withdrawal-symptoms. (Fish oil may be more helpful than krill oil.)
There's a lot of info on this blog–it is worth your time to read it all. Also, you can click on anyone's name and read just their posts.
@clg this is exactly what I did. It took me a month to get off Venlafaxine and this helped so much! The withdrawal was definitely there, but it was manageable!
All the best!
Did you try breaking open the Venlafaxine capsule and tapering your dose from 37.5mg? Each white tablet is 12.5 mg there’s 6 tablets in the 37.5mg capsule (this is for Venlafaxine not Effexor) once I got to one tablet I stopped taking it from there! It definitely sounds like you’re going through Venlafaxine withdrawal, maybe add a few white tablets in to help ease the symptoms?
This community forum is incredible and such a safe place to talk and discuss how your feeling! Know you’re not alone in this process! Share your thoughts and worries and we can support you on them! Most of us on here have been through it too!
Good luck & we’re here for you 💜
Thanks for the encouragement. It seems things are getting brighter and lighter. Probably accomplished more in the last week than I have in the last 6 months, and everything isn't out to get me anymore. It feels great to be able to sleep, actually sleep and not be chasing horrible thoughts and dreams. Still powering out both mentally and physically for no reason at the weirdest times but it hasn't been that long without effexor, 3 weeks.
The biggest revelation is understanding how off, how sick, how nasty I was, and the extent of physical effect the withdrawal and crash had on this poor old body. A challenge is explaining to others that we don't control our brains and how they work. We work along with them and are lucky to be able to predict what they might do but when something is wrong, because of a drug or ??, we can only try to keep up and stay safe. I have new respect for the thing inside my skull. It seems to have a life of its own.
The wanting to dissolve off the earth feeling is not there all the time and yet everything that overwhelmed 3 weeks ago still is. It is crazy following your own thoughts and your own brain sometimes...what will it do next??
I feel like we are in the same boat.. about 2.5weeks off here and a lot of what you say resonates.. like is this the drug? Or am I gonna be like this forever.. when I first stopped I wasn’t sleeping l, and realized also I had stopped taking my thyroid med (armour) I was having crazy ocd and intrusive thoughts issues.. when I started taking g it again, they subsided.. coincidence? I hope not but that demonstrates the confusion we can get on this stuff...
Cheers and keep it up
@jakedduck1- Jake, Spot on! Thanks for once again making it crystal clear. Jim@thankful
Where are these peoples doctors? Are these docs that ignorant? Are people just waking up one morning and deciding to just stop taking meds they’ve been on for years? I don’t get it.