Anyone on Pluvicto? Looking for a support team

Please do keep us posted! We are all interested in how you do, and everyone can benefit from learning about your Pluvicto experiences.
And one thing to add about side effects: my husband also has had some mild gastrointestinal issues such as constipation for a few days after the infusion. Miralax clears that up quickly.

Hi @nhs61, I moved your post to this related discussion:
- Anyone on Pluvicto? Looking for a support team
https://connect.mayoclinic.org/discussion/anyone-on-pluvicto/
I did this so that you connect with others like @eugenelapietra1 @bicio58 @digger @redroadtraveler @kjbushur a@lcoleman3 nd others in addition to the helpful posts you've already received from @lag and @lisab2.

You may also be interested in the discussions I found using the group search:
https://connect.mayoclinic.org/group/prostate-cancer/
@nhs61, how many treatments have you had so far? Any side effects?

I saw somewhere on here but now can not find a gentleman that was going to start a trial of sorts with a second round of Pluvicto after completing the initial 6 cycles. I wanted to see how he did on this as my husband just completed his 6 th dose today at MDA .Does anyone have knowledge on this man’s outcome or can you direct me to him?

I remember reading the same thing with interest, because I started Pluvicto Dec 2023 and had great results, but I'm always looking ahead to possible options.
Prayers for all on this journey and their partners. I'll check the Mayo site for any references and forward if successful.
Blessings

I'm the Pluvicto repeat patient you are looking for. I was a clinical trial patient at the University of Chicago Medical Center for PSMA 617 LU177 in 2021-22 for Novartis Pharmaceutical. The USFDA approved the program in about late 2022 or 23 under the name Pluvicto. About 25 months later in 2024 and after exhausting other treatment options, arrangements were made with Novartis, Medicare, my supplemental insurance and my oncologist to repeat the 6 treatments. I've received 4 of the repeat 6. And, I am extremely happy to say, my response is, once again, remarkable. So much so, treatments 5 and 6 are temporarily paused to help reduce unwanted side effects and the remaining treatments can be administered at a later date.
This is a very rare situation, as insurance will only pay once. Since the first round of 6 treatments was a trial paid by the pharmaceutical company, the insurance providers viewed this 2nd round at their first. It is completely at my own risk. I'm kicking the perverbial cancer can down the road a little further, hopefully another couple of years.
Perhaps, by the time you need a second round (or I a 3rd), approval my be in place for this life saving treatment.
Stay in touch. I'm as curious about you as you are about me.

Ontario approved it and my hospital will provide CVH Mississauga It even works better if one had Radium 223 which I have On Abiraterone now but PSA flared to 218 concerned Just did PSMA PET scan for qualifying for LU 177

My husband is starting Pluvicto in a couple of weeks. I wish I could do more other than sending love, light and healing to you. I know it must be hard after losing your wife and not having a close suppport from friends and family.

My husband cannot drive himself home after second Pluvicto treatment on Wednesday 3/5. Called the office to see if (husband) riding in the backseat is enough. Have not heard back. Protective clothing??? Any suggestions?

PSMA PET verified that I am a go for LU 177 with C in T 11 and L4 and hips May start in April at CVH Still on Abiraterone with Prednisone and just took Xgeva and Zolodex injections

Prayers daily 36% OS of 24 months they say with L:U 177

I've been through Pluvicto and am in the process of repeating the treatments. The guidelines say stay 3 feet or more away for the first 3 days, for extended periods of time. My recommendation is to have him sit in the back on the passenger side, opposite the driver . Moisture, when exhaled will be radioactive (as is urine, sweat, etc). Keep the heater/air conditioning FAN on medium or higher. This will bring in the most outside air, maintaing positive pressure inside the car, which forces the air out through the louvers in the back (trunk). DO NOT use the recirculation setting. You want all fresh outside air. Depending on the weather, a partially open window would be helpful to get rid of the contaminated air.
While in the hospital, watch the medical staff. It's not as scary as you might think, but definitely follow the guidelines.