Ivermectin for Prostate Cancer? (Being studied)

Oh, going overseas to some countries is inviting a parasitic infection, as you point out. I’ve heard some real horror stories!
The reason I don’t do Ivermectin now - besides my belief that it is not proven yet for PCa - is that I am currently on Orgovyx for recurrence with radiation to follow. In just one month my PSA has gone from .18 to .05 and my testosterone from 609 to 5. Five more months can only enhance its ability to starve the cancer cells.
With that kind of result why would I try something that has never been tested in double blind studies? Why add a possible as yet unknown drug interaction? Why fix it if it ain’t broke?
Ivermectin and others surely have promise - I’ve read of their ability to inhibit certain functions in cancer cells of all types; it definitely needs to be explored in greater depth. I have no doubt that if this inexpensive drug could be turned into a multi billion dollar powerhouse, Big Pharma would molecularly tweak it just enough to avoid any patent disputes and sell it like crazy with a catchy name.

@vancouverislandhiker, thank you for adding "with your doctor's approval". You're also correct that ivermectin and related anti-parasitic medications have been on the market for years. However, this does not make them safe for all conditions.

I add a caution about the statement "trying it can't hurt you." Repurposing drugs for conditions for which they are not approved may be benign (have no effect), cause unwanted symptoms, be irrevesibly harmful or, in some cases, be fatal. So back to your statement about talking with your doctor when considering off-label medications.

I know you guys are going to find me annoying 😁, but I have to repeat the community guidelines https://connect.mayoclinic.org/blog/about-connect/tab/community-guidelines/.

A recap in blunt and brief:
1. Don't prescribe or tell people what to do.
2. Never disregard professional medical advice or delay in seeking it because of something you have read on the community.
3. Keep politics out of the community conversations.

Best of luck with things . Always check with your doctor before trying new things . I started using a new Pre-workout powder , great stuff that the Dr said was OK for me ... but I noticed that it had 'testosterone enhancing ' drugs in it . I questions him again , and he said maybe switch back to the other one I used . I scrapped them both and just have a coffee before the workout for the extra gas in the tank . I guess my point is even Dr's cannot keep up with every substance on the market . God Bless and good luck with Orgovyx. Heard some good things about it , depleting testosterone .

Any help with Stage IV prostate metastasized. nothing is working. Anyone try Ivermectin or other non conventional drugs?

@topsz, I moved your question to this existing discussion so you can read comments from fellow members:
- Ivermectin for Prostate Cancer? (Being studied) https://connect.mayoclinic.org/discussion/ivermectin-for-prostate-cancer/

The short answer is researchers are studying Ivermectin to see if it may be used as an anti-cancer drug and early studies show promise. Please note that this research is in the early stages (mice studies) and has not yet been tested in human trials. Ivermectin is not a proven standard treatment for prostate cancer.

Important
It is NOT safe to take ivermectin used in veterinary medicine. Please talk to your doctor before taking any over-the-counter medications or supplements that claim to fight or cure cancer.

Hey buddy, There are lots of anecdotal stories on the net about Ivermectin but so far they’re just stories.
I totally get where you’re coming from - try anything at this point, right? But this is probably not the answer. I don’t know what treatments you’ve had but some guys on this forum have had “triplet therapy” using chemo in combination with specific hormone drugs or Pluvicto.
Just to respectfully ask, were you treated at a center of excellence - like a Mayo, Sloan, Andersen type center- or by your local doc/urologist? Going to one of these hospitals can make a much greater impact on your longevity than some unproven dewormer. Best
Phil

U of M. Yes at that point.

U of M is a good one….even chemo had no effect?

Never was offered that. Radiation and different drugs. Now hemoglobin is low and they won’t treat cancer. Too dangerous they say. Only blood transfusions which isn’t going to help stop cancer growth.

My own PSA rose from 7.9 in October '24 to 10.5 in January '25. I'm worried; looks like mine is more aggressive than yours (8.1 to 9.6 in six months), mentioned in tvz 2014 post.
My primary care physician referred me to a urologist who took biopsy specimens on Feb 14, 2025; tests result is a Gleason score of 7 (3+4). The uro has referred me to an oncologist, who will see me for my initial consultation next week.
I am hoping for the best, that the oncologist can help/lead me to the right treatment. Those of you in this support group, who also had a Gleason score of 7 (3+4), care to share your journey?