Timing of Tymlos Injection-AM vs PM
I just started Tymlos this week. I really would prefer to inject at night, but read a study on Forteo (the other PTH analog for OP) that showed significantly better results among people who injected in the morning vs. those who injected in the evenings. Does anyone have any relevant experience or insight? I know the company doesn't suggest any particular time of day, only that it be consistent. Thanks!
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Hi @mary1951 . I sadly had to quit taking Tymlos after 3 months due to hypercalciuria-high urine calcium. Turns out I have the issue at baseline and Tymlos doubled it. It should have been tested before I started on Tymlos. Such a shame, as my P1NP had doubled at the three month mark. I think it’s a remarkable drug and I hope you get great results!
Hi Marymj7,
Thanks so much for responding to my question. I'm sorry you had that side effect though! I know that can be serious! It's a good thing your doctor was testing you regularly for it, or did you have symptoms?
Did you go on to another drug?
That's very encouraging that you had such a good increase in only 3 months, though!
This encourages me tremendously. Thanks again.
What does your doctor say about how to treat the fast heartbeat and low blood pressure symptoms? Thanks so much.
@mary1951 I had some dizziness but my doctor tested me at the 3 month mark because that is protocol. I am eating low sodium to try to get the urine calcium down. I don’t think any drug will help much until or unless I can stop losing so much calcium
@susanjohnston, I can't say my endocrinologist has been very helpful in giving advice. I sent some messages through my portal to him with some questions about the fact that my blood calcium levels are typically on the higher side of normal, and having tests done before I started Tymlos, and he pretty much blew me off. He wants to see me in a year, which I think is ridiculous. Taking a powerful drug like Tymlos, I would have at least hoped he'd want to check my blood levels in 6 months!
Anyhow, the people on this site have helped much more than the doctor and nurse, who was very rude when I asked her questions about how to do the injections. So I listened to @windyshores and @gently and drink a couple glasses of water before hand and eat something salty before hand as well, and I believe that has helped. My blood pressure is normally low, so I am used to eating salty stuff during the day, even though I know salt is not good for you. In my case, I seem to need it. I have had hyponatremia multiple times, and once ended up in the hospital almost in a coma from it, so I am used to eating salty stuff whenever I feel symptoms starting, or see that my blood pressure is lower than my normal.
The rapid heartbeat is also something I am used to, so I don't worry about it, as it is short-lived. But I think I read on this site that someone said elevating the feet above the heart helps. I have an adjustable bed, so I have been elevating my feet for about 20 minutes after the shot and that does help.
Hope that helps.
@mary1951, I am so glad that you were tested! My endocrinologist doesn't want to see me for a year! So no tests.
I guess I'll need to monitor myself for symptoms, ad unfortunately, if salt is a culprit, I am a big candidate for urine calcium problems, since I crave and eat a lot of salty foods, due to a history of hyponatremia and low blood pressure.
Thanks for responding and do take care!
Thanks so much for your thorough and helpful response.