Jak2 positive, biopsy next: Does it mean I have blood cancer?
Hi, I've been told I'm jak2 positive. I'm due to have a bone marrow biopsy in a day or two. My question is, if it comes back normal does it still mean I have some kind of blood cancer?
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24 Hydroxyurea capsules seems an extreme dose, Hope he is able to lower the dose quickly, Best wishes go out to you.
Not sure of your stated dosage intake. How many 500 mg (HU) are you taking per day?
I started with one per day and after several weeks my platelet count decreased to 350 from 970. My Hemo/Onc reduced HU to 4 per week and I’m holding my platelet count at 350 for the last 8 months. All other blood values are in spec. No side effects except for an increase of skin lesions (squamous cell carcinoma). I had two removed from my hands last week. Small price to pay in order keep JAK-2 at bay.
I started on HU, 500mg/day a month ago . Platelets decreased from 650 to 450; Onc/Hem. She almost increased my HU , but will re-check blood in 6 weeks . I’m praying my platelets decrease . I’m 69, only have a few mouth sores, night sweats and leg sores, otherwise I feel great .
Anyone have any ideas about extra things I can do to get the platelets down besides increasing HU? I exercise , eat healthy , weigh 110, only have Osteoporosis, still work 3 days/wk. I dread increasing HU . Help!
Me too ; didn’t want to say “cancer” or take HU for the rest of my life , but the risks without it are much worse . Stroke run in my family ; ET is not genetic , but studies are still being done to determine if it is a precursor in families. ( My Aunt and Uncle were on HU and both had strokes )???. Best of luck !
Standard dosing for HU is usually one per day. It takes a few weeks for your body to adjust. Don’t expect overnight miracles. Diet and exercise always have a positive effect, so stay with the program. I’m 88 and I’m living my life. Essential thrombocytopenia is just a minor inconvenience as far as I’m concerned. Good luck in the future.