Tips on minimizing withdrawal symptoms from Effexor (aka Venlafaxine)
I have been taking Effexor/Venlafaxine for years and tried to get off it a few times but each time I try to give up the chemical withdrawal symptoms are a horror story and I give up giving up. Anyone got any tips or tried and tested strategies? Thank you
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I'm sorry to hear that. Did you find anything that helped?
ER will be a capsule -- the non extended release are tablets you can split. Your experience of missing a couple of days is very consistent with what I've had over the years - especially the weird dreams...the nausea, etc can also happen.
I don't believe there is any particular correlation between dosage and the magnitude or duration of withdrawal symptoms....I didn't really have any symptoms until I got down to 37.5mg (from 150mg - both in the ER form) and then those symptoms were worse once I tapered to zero after about 3 weeks at 37.5. My taper was supposed to happen more quickly - but I chose to slow it down because of the withdrawal symptoms and my difficulty getting work done.
Can't offer you any advice on your concerns over SAD in the winter and a taper....SAD has never been part of my pathology. However, re; being past menopause -- one can still have menopause like symptoms years after menopause officially occurs....it's like post-perimenopause...but my guess is any menopause-like symptoms will be less frequent and intense.
There's probably no downside to taking the pills indefinitely - but that is a question for your physician. Although I recently read that there is potentially a correlation between SNRIs (Effexor, Cymbalta) and glaucoma risk. This came up when my ophthalmologist decided to watch me more closely for glaucoma. I've been suspect for decades because of my anatomy - so it will be interesting to see what if any changes he sees after I've been off Effexor for 6 months...but I think the data is pretty spotty at this point - and it wouldn't change whether or not he would start treatment.
Don't disagree with you at all. There is clearly a way to get approval....and some companies are better than others. I've been aware of a researcher at Columbia who for years has asserted that the SSRIs are basically no better than placebo for many people. And you are definitely right in your interpretation of the rule changes....although economics play into it as well. Before we got to the say, late 80s, pharma companies were generally guaranteed a decent return on investment for drugs that could get approval. But then the model shifted towards seeking approval for drugs that weren't significantly better than currently available drugs - hence why there are a billion different types of SSRIs/SNRIs (and the same in other classes) -- It's been a long time since the pharma industry came up with a revolutionary drug class that many people would take for long periods of time....Most of the SSRIs/SNRIs are off patent now -- so other than a few companies trying to milk this class with new products - the pharma companies seem to be focused on getting people to take atypical antidepressants along with their SSRIs for "treatment resistant" depression/anxiety. Now there are certainly some people who will benefit from the atypicals -- but those do have well documented side effects - particularly in terms of cardiovascular (high cholesterol) and if memory serves, diabetic risk as well.
Hello Mardi. Thank you so much for your advice. I have been taking effexor 150mgs for approx. 35 years and I am currently down to 375mgs, after three months. Struggling with headache's, nausea, anxiety, irritability, fever's, chills, short term memory loss; the list goes on ! Have only just told my adult son what I am going through (I had not told him that I suffer from depression ) Have kept this as a secret from everyone, as there is still a negative stigma attached to this issue in Australia. I have found that hard exercise helps me greatly. I find it difficult to be around people, and get agitated easily. I am really determined to succeed and found your advice very beneficial.many thanks Shoshi x
Hi All! Do these withdrawal symptoms ever go away?? I am so miserable. 🙁
Hello! I am not sure how to post so I’m just replying. First I’d like to say YAY!!!!! I am so excited to find people that know what being on Effexor is like!!! I have been on and off Effexor for 20 years now, each other time I got off I was only on a max dose of 150mg. This time I’m on 225mg for the past 2 1/2 years. I appreciate all of your input/ sharing of experiences!!!
My question is this, in your experience have you found this med to cause sudden onset of sweating? And have you found it to numb you? I know it keeps you from going down but I feel like it keeps me from going up too. Thus the wanting to get off, I am working with a psychiatrist but prefer first hand experience even though I do realize everyone is different. Thank you for your time!
Jo
Good to know! Thanks
This doesn’t surprise me.
15 years at 150mg (extended release)....but completely off for nearly 10 days on a 4-5 week taper. Sweating when I tapered - YUP (I think I bought most of the icepacks on Amazon)..... I usually get some facial numbing going up or down on the drug - but I suspect you may be speaking about emotional blunting. In that case, Effexor can mellow the top end (I've had experiences of feeling really good and productive when I've cut my dose for a few days to try and reboot the drug at my old dose)....but that's not it's primary function....and the emotional blunting is something I believe gets reported for all the SSRIs.
Yes , all SSRIs cause emotional blunting , in some cases that is a good .