Evenity Contraindications for Cardiac Issues

@windyshores Thanks again for weighing in. I watched Dr. Leder's YouTube lecture, was surprised to find I followed most of it, but am going to have to watch again to make sure I got things right. He is really impressive!

I am going for a lipid study this week -- I have high cholesterol and have been on Pravastatin, and need to see how well (or not) it's working. (I noticed one article stating high cholesterol seems to be a risk factor where Evenity is concerned.) I think I will feel more comfortable about it if my numbers are good.

Thank you. I appreciate that. It’s all somewhat overwhelming right now and I’m just trying to understand and get as much info I can. Figuring it out and how it pertains to my situation

I have cardiomyopathy and an implanted pacemaker/defibrillator.

I've been prescribed Evenity - it's the first bone building medicine I've taken, and I'm very worried about the danger to my heart. Does anyone have any information on how dangerous the heart risk really is?

Thanks!

*corrected*
hi, nemorose. If you have existing cardiac issues, choose a different medication. The FDA does give us a big black box warning.
I'm waiting for the real world results to play out and that may take decades.
Maybe the black box will be eventually be removed.
The easy thing about Evenity is the every month injection, and that most insurance pay for it without hassle.
Other side effects discourage me. But some don't experience any extra aches and pains.
I'd encourage Forteo or Tymlos as a medication to start.
Bless your choice.
https://www.bbc.com/news/uk-england-bristol-65765591

Prolia is injection ever 6 mo.
Evenity is monthly injections

I want to start Evenly but Rheumatologist wants me to start Reclast due to the warning of heart problem black box warning. No heart problems but I do have high BP. Also, I thought Evenity was one injection every month for 12 months? Good luck!

For context: I’m a 60 year old, healthy, active, petite woman. Three years ago, I have developed unexplained mild tachycardia that cardiologists have told me and continue to tell me not to worry about. My blood pressure has always been on the low side of normal.

A little over a year ago, I was diagnosed with osteoporosis in my lumbar spine, hip, and femoral neck. The worst was my T-score for my lumbar spine was -3.5. I went ahead with my endocrinologist’s recommendation of Evenity first to build up bone, to be followed by a different drug to help maintain it. I just completed my course of Evenity in December (2 injections every 28 days, for a year.) I did not have any symptoms at all with the exception of mild soreness at the injection sites. No changes to my heart.

I just got my DEXA scan results a few days ago and the most significant change is my T-score for my lumbar spine (done by the same technician on the same machine) improved from -3.5 to -2.4, moving me from osteoporosis to the osteopenia category. I was happily surprised by the results. (My T-score for my hip improved slightly and my femoral neck worsened slightly. Both still in the osteoporosis category.)

I will say that I took it upon myself to work with a nutritionist to learn what foods contribute to or rob my body of calcium, and the importance of Vitamin K2 to help direct calcium to the bones, and Magnesium to help absorb calcium (along with Vitamin D) and I also took it upon myself work with a physical therapist to strengthen my core. I believe doing these things have contributed to my improved results with my lumbar spine and hip.

(BTW, I had my first Reclast infusion three weeks ago and have had horrible side effects. I have a follow-up appointment with my endocrinologist this week to discuss them.)

Good luck.

There is a cardiac warning on Evenity. However, I have cardiomyopathy and my cardiologist said he would be fine with my going on the drug -- he felt it didn't present a risk in my case. If you have concerns, you should consult a cardiologist before using the drug.

I am getting ready for my 2nd dose tomorrow. Surprised I only felt a bit more achy in my lower back and hips. But that could be the cold month of January. I have upped my calcium and D and also doing collagen and working my mind set to get more exercise. That’s the tuff one. Will keep posting progress.