Effexor Withdrawal Side Effects

Posted by vicdenlee @vicdenlee, Jan 1 2:41pm

I need encouragement and hope from those who have experienced side effects from tapering off effexor and how long you were on it, how long it took to taper and how long it took for all side effects to go away!
I am struggling to stay motivated and encouraged to push myself to move through the day! I am anxious when I wake and anxious when I go to bed. I am journaling, praying and trying to use MUSE for relaxing/calming my breathing due to anxiousness. I have an appointment with a psychiatrist, but it is a month away due to availability.
I discontinued the effexor after tapering off 75mg after 17 years due to some increased side effects I was concerned about. I was originally put on it when I experienced some peri-menopause symptoms--extreme night sweats, moodiness, anxiety and panic attacks in my late 40's.
After the last day of tapering(a very short taper unfortunately as the doc I saw convinced me my dose was so low all these years that the side effect would be minimal if non-existant.). I experienced terrible flu symptoms--nauseousness, chills, sweats, dizziness, headache, lack of concentration, etc. Luckily the headaches went away and after 8 weeks I now feel like I can concentrate some better. The chills and sweats are lighter and not as frequent. The nauseousness is not good. My husband baked oatmeal scotchies this morning and the sweet surgary smell made me gag! I am mostly anxious--what will go wrong, how to relax? I feel like I need something to tone this down but not sure what to ask for. Doc suggested yesterday, I combined hydrochloride and busipar to relieve the symptoms. Not sure I trust him since he said I wouldn't have any side effects and didn't want to listen to my concerns about withdrawal side effects in the first place. Even the pharmacist I spoke with indicated my dose was so low it would be really easy to taper off. I am sleepy but don't want to go to sleep during the day so I can make sure I sleep at night.
I was crying quite frequently at almost anything sad, even thinking anything sad. Emotions are dysregulated. I am trying to exercise more, drink more fluid, take my vitaming D which is extremely low due to being on the effexor so long.
Today, I filled out a bunch of paperwork and felt pretty good glued to the chair and concentrating on getting it done, but the minute I knew I needed to make lunch or get up to interact with others, or just think about the symptoms of this withdrawal, I become anxious and lose concentration.

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@thatgirltrish

I’m so sorry for your struggles with discontinuing an SSRI. Hang in there as it will get better.
I am 70 years old and have been prescribed Paxil (40mg) for 15 years. My depression is serious and Honestly it was a life saver! Last summer my physician let me know that studies indicate this drug could cause - or worsen - dementia and it was time for me to stop. I began researching withdrawal side effects and was not happy as there were horror stories.
My MD wanted me to decrease by 10mg for 2 weeks then another 10…
I insisted that I would take it much more slowly starting with a 5mg reduction for several weeks.
I read one story where it took someone a year to completely discontinue an anti depressant so I felt encouraged by that.
My point is just that - don’t rush! I am down from 40mg to 15mg and feeling good. It might take 4 or 5 more months to complete and that’s okay.
Good luck and just know you are not alone.

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Thanks so much for your reply. I should have also mentioned that I really can't reduce my effexor slowly due to the fact that it has caused liver damage. I need to discontinue ASAP. I actually had a liver biopsy today to determine the extent of the damage. This is all so scary and I appreciate you saying it will get better. Sometimes, it sure doesn't feel like it!

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You are so brave! I've been on Effexor XR for twenty (or more?) years and at this point going off of it has not even become a discussion with my psychiatrist or therapist. If I forget to take it immediately after waking, I definitely notice within a few hours. Brain zaps, very strange yawning, feeling a bit faint.

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@benegesserit

You are so brave! I've been on Effexor XR for twenty (or more?) years and at this point going off of it has not even become a discussion with my psychiatrist or therapist. If I forget to take it immediately after waking, I definitely notice within a few hours. Brain zaps, very strange yawning, feeling a bit faint.

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I am trying to taper off effexor, I am prescribed alprazolam.25mg as I take as needed, not often. Have you tried benzodiazepines to help Withdrawal?

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@sliffer

I am trying to taper off effexor, I am prescribed alprazolam.25mg as I take as needed, not often. Have you tried benzodiazepines to help Withdrawal?

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The doctors won't let me take anything right now, because nearly all meds are metabolized by the liver. I can't believe this is my life right now.

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@mmsm

The doctors won't let me take anything right now, because nearly all meds are metabolized by the liver. I can't believe this is my life right now.

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Oh no, I have not talked to my doctor yet, I had been really sick with RSV and kept forgetting to take my nighttime effexor. I also take tramadol for severe back pain that does help. I can't believe the doctor won't give you anything, my bff wanted off effexor and her doctor have her welbutrin. Prayers for you

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It’s sad but encouraging reading other people’s experiences with Effexor, I’ve been on 150mg twice daily for near ten years for depression and had no idea how huge that dose was. I’ve been dealing with Bruxism or grinding my teeth/clinching my jaw in my sleep and migraines for years as well and recently discovered theyre connected to high doses of Effexor. I’ve been hesitant to consider lowering the dosage because of the side effects of accidentally missing a day or two the bad headaches and shocks in my brain I get, but perhaps just a very prolonged decrease will do the trick

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I wanted to give an update and just say to everyone to hang in there!! Get the support you need and keeping pushing yourself--fight! Tapering off the effexor was one of the best and one of the worst things I've ever done! The journey can be difficult but also, very freeing! I am just now feeling more and more like myself after six months and still imagine I will continue to improve. It has been an emotional ride. But, I have used the book/workbook by Craig Groeschel, "Winning the War in Your Mind". It has been a tremendous help and I have had success using some of the tools he mentions such as "framing, reframing and preframing". He explains information about how our amygdala and prefrontal cortex work in controlling our mind and our emotional responses. I don't know about you but the more facts I have the better I understand how to heal my brain. Because, that is what you are doing is healing your brain and giving it time to reregulate itself. But, you must help reregulate it in a positive direction!! So repetition of giving yourself positive feedback, giving yourself lots of grace, taking care of your body through exercise(no matter how slow or out of shape you are, just move), and eating correctly and drinking lots of water--think about detoxing your body and breathing in good and exhaling bad! After a long wait, I was able to get into an Ob-gyn/Psychologist. She has been fabulous to recommend different supplements my body was lacking through doing the correct bloodwork. I had already been low on Vitamin D, but now also take a Super Vitamin B Complex, Magnesium Glycinate, Fish Oil(not krill oil), Calcium. I would recommend adding one at a time to be sure your body doesn't have any reactions to each supplement and to definitely speak to your doctor about how much to take--we're all different. Be sure the laboratories your supplements are made in are in the US and regulated by a third party. Try to obtain as "clean" of a vitamin as possible without all the extra stuff some companies add to them. We are now also looking at my hormone levels and trying to decide if I should try hormone replacement. The supplements my physician recommended all help the brain and help regulate mood and anxiousness!! BUT, besides the book, the supplements, a good doctor, ... obtain support from a counselor and don't be afraid to walk away from them if they don't understand what you're going through. I have tried four different counselors--only two of them understood the effexor withdrawal and believed me(unfortunately the first one died unexpectedly during this process). The other two counselors just wanted me to talk talk talk so they could psycho analyze my childhood. I needed a counselor who would not only listen, but also someone who could offer facts, concrete tools/skills to learn to regulate my brain again. As one counselor explained--the effexor controlled all the highs and lows in my life for years and now the brain without it, was saying "help!, no one is telling me how to react". Understanding that I needed to start telling my brain how to react and practicing, repetitiously practicing how to react has been the most helpful. My new normal going off the effexor, was to cry about everything--happy, sad, angry. This has been the hardest to fight through. Forgive yourself, give yourself grace and if you need a nap or time out to go for a brief walk, take it! Then start again. Give yourself small positive talks for achieving small things--take courage and take victory, don't be afraid. Mornings and evenings had been my hard times initially. And then there would be days, that all I'd focus on would be wondering when the anxiousness would subside, which as you know causes more anxiousness. But, I'm evidence of pushing through and you can do this too!! Make yourself get up and exercise--whatever you enjoy as a physical movement or come up with something new and joyful, like bike riding or dancing around your living room(physical exercise helpf increase serotonin which you need). The process can be a roller coaster, but hang in there. I have had a difficult time listening to and watching action movies and extensive drama shows. It was just too much for my brain. My brain had a hard time handling all the quick changes in emotion. I know this sounds strange and I thought it was just me reacting strangely, but I did find others who have had this same response off the effexor. One person said all she could watch for the longest time, was cartoons. So maybe be prepared to take a break from too much drama on the tv or facebook or the news--I'm just now starting to be able to handle listening to US and world news reports because I felt they were all doomsday reports. I have felt fearful about my children living so far away from me even though they lived far away when they were in college and now in there careers for some years. That fear is greatly subsided but I still need to be careful not to dwell on it. So get a good counselor and ask them to help you practice emptying your mind of negative thoughts and then telling your mind to stop, and move on to healthier topics. You can do this! Personally my faith in God has been helpful, but you will all have to decide what helps you best! I hope your families and friends are patient with you! Be patient with yourself and remember to celebrate the small hurdles! I'm now able to get up in the morning and feel positive about my day. I try to look at my schedule the night before and come up with at least one thing where I can focus my energy and have a positive outcome the next day! I hope this is helpful!!

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