My oncologist is also happy with my numbers in the 500s and uses incremental dosing too. I was at 800 two years ago; now in the 500s. Overall, blood work big picture is better. I take baby aspirin in the AM and PM, 500 mg of HU 4x a week, and a daily iron supplement due to low iron but not anemic. I have no symptoms; just high platelets. Friday, I have corneal surgery at Hopkins and I am off baby aspirin, then off HU during recovery. I am nervous about being off the meds. Last year I was nervous being on the meds. Trying to stay calm and live my best life at 71 with 5 wonderful, young grandchildren. My best to all!
Karla