MGUS and quite high Free Kappa Light Chain and Kappa Lambda Ratio

When either of your kappa or lambda serum reaches 100

My IgA kappa MGUS was diagnosed when my kappa was less than 30 (normal is 3.30 - 19.40 mg/L), 8 years ago. It is now 329, and my deranged plasma levels are 15% based on my recent bone marrow biopsy. My MGUS is still MGUS based on looking at all my bloodwork, lack of lesions or other damage, and limitations of BMB (proteins are sticky and tend to clump, so plasma levels are likely less than 15%). That is why having an oncologist/hematologist is important, MGUS, SMM, and MM are like 4D puzzles with pieces missing.

Ok what does that mean

Both my kappa and my lambda are at 200 and the ratio between them both is 99 should something be done. My oncologist says we just monitor it

So I was diagnosed with MGUS about 5 yrs ago and both my kappa and my lambda are at 2.00 and the ratio between them is 99 is this bad what does this mean

@salik74 was not correct. My oncologist told me that my kappa levels would probably need to be in thousands before SMM or MM were diagnosed; technically, SMM and MM are more complicated than the numbers of one or two tests. I've had IgA kappa MGUS for 8 years and my kappa is now 329 and kappa/lambda almost 30 (my lambda is normal range, my kappa is not, so that affects the ratio). It would be good to pin down your oncologist and have him/her go over all your tests and explain what they mean. The chance of MGUS morphing to SMM or MM is 1%/year so doctors don't always realize how much the MGUS label can slap us around emotionally.

My doctor is watching my Kappa Lambda serum which is
45. 7 & I am still SMM. He stated when or if it reaches 100 then I start
treatment.
These go up & down every 3 months with labs.
I would say you still don't need treatment

Unless you are her oncologist, it isn't appropriate for you to say she "still don't need treatment". Every MGUS, SMM, MM case is different because it is a very complicated condition/cancer that has a lot of variables. That is good that you are still SMM and hopefully it never progresses, but your case is not hers.

You are correct it is complicated & everyone is different.
There are many different tests to show where you are in this disease.
I appreciate you correction

@rebeccaakabeck
Yes, I may have missed your response, but I caught that you are seeing a Physical therapist, but were you also referred to a hematologist/oncologist? Sorry if I missed your response.