I have a similar diagnosis, but I am high risk due to over age 60. I took baby aspirin for 30 years for sticky blood before getting the diagnosis of ET/Jak2. What is your platelet level? What is your allele burden from Jak 2? If platelets over a million and/or high allele burden, I would definitely start the HU. By the way, I take baby aspirin AM and PM, and HU 500 mg 4x week. My platelets were 800K in Jan 2023 and now about 550K. I have no other symptoms. My O/H is happy with my numbers, plus he looks at all the other blood work to determine that I am stable. He checks my spleen (palpitates) at each visit. I also take iron supplements for low iron but not anemic. Make sure you have blood studies for iron checked. I see my H/O every 2 to 3 months. I belong to several online groups that have monthly, free online seminars with MPN doctors. I highly recommend joining the (free) MPN Research Foundation and the MPN Advocacy and Education. The MPN specialists to follow: Dr. Reuben Mesa, Dr. Aaron Gerds, and Dr. Gabby Hobbs.

Wishing you the best. You can live a good life with this for a long time. I'm 71 and doing great!
Karla

Join these great organizations for free:
https://mpnresearchfoundation.org/
https://mpnadvocacy.com/