Innovative Peptide based eye drops for dry AMD

Posted by prayingtolucy @prayingtolucy, 1 day ago

Anyone hear about this?
I've been reading about it and it could be approved to treat dry AMD in the not too far future.
This is something else for me to discuss with my specialist.

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I had very dry eyes many years ago but they are now better.
At Mayo optical store they started eye goggles to wear. I think the name is EyeEco. You put your eye ointment on when you go to bed, then put the goggles on when you get into bed.
Within 3 to 4 months after I bought my first goggles I called the clinic. It said somethings wrong. My trifocals were blurry, and I couldn’t see with my glasses on. Upon an eye check, they told me I didn’t need my glasses anymore .
It has been over 20 years since I started this path and now I have glasses again.
But my eyes don’t hurt as bad and they do have moisture in them.
I wish you the very best.
Google EyeEco. You could also call him and they are very nice to work with

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@minnesota10

I had very dry eyes many years ago but they are now better.
At Mayo optical store they started eye goggles to wear. I think the name is EyeEco. You put your eye ointment on when you go to bed, then put the goggles on when you get into bed.
Within 3 to 4 months after I bought my first goggles I called the clinic. It said somethings wrong. My trifocals were blurry, and I couldn’t see with my glasses on. Upon an eye check, they told me I didn’t need my glasses anymore .
It has been over 20 years since I started this path and now I have glasses again.
But my eyes don’t hurt as bad and they do have moisture in them.
I wish you the very best.
Google EyeEco. You could also call him and they are very nice to work with

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Wet and Dry AMD are two different conditions. Dry AMD does not mean you have dry eyes it means your AMD is not involving a vascular component. I have intermediate dry AMD but I don't have dry eyes or need eye drops to lubricate the eyes.

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There are no US studies on peptides and dry AMD. There are Russian studies and an over the counter product can be found online to purchase but it is weaker and no FDA approval or marketing is being considered. There are US studies you can easily google on Melatonin, Turmeric, Saffron, PQQ, NMN and CoQ10 as being protective and possibly delaying the progression of the disease. I take MitoQ formula CoQ10 for eyes. I take them all as well as Areds2. I found the NIH studies on low dose rapamyacin and AMD and have a prescription for low dose longevity 5 mg rapamyacin weekly. This is not an eye injection. You can use chatGPT to find out more about these US studies. Areds2 is the gold standard . I can’t provide links to these studies here.

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I'm not sure where you got that information and I'm not doubting you but why am I finding that the US is researching it? For example;
"Yes, the United States is researching peptide-based eye drops for treating eye diseases like dry AMD. Peptide-based eye drops are a promising treatment option because they can be delivered non invasively and can be more effective than small-molecule drugs."

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@prayingtolucy

I'm not sure where you got that information and I'm not doubting you but why am I finding that the US is researching it? For example;
"Yes, the United States is researching peptide-based eye drops for treating eye diseases like dry AMD. Peptide-based eye drops are a promising treatment option because they can be delivered non invasively and can be more effective than small-molecule drugs."

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ChatGPT

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@prayingtolucy

I'm not sure where you got that information and I'm not doubting you but why am I finding that the US is researching it? For example;
"Yes, the United States is researching peptide-based eye drops for treating eye diseases like dry AMD. Peptide-based eye drops are a promising treatment option because they can be delivered non invasively and can be more effective than small-molecule drugs."

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investigated the use of a Fas-blocking peptide administered via eye drops. This research demonstrated that the peptide could reach the retina and mitigate degeneration by modulating inflammatory cytokines and inhibiting Fas-mediated apoptosis in animal models. The findings suggest potential therapeutic applications for dry AMD, though further studies are needed to assess its efficacy in humans.
PUBMED

Additionally, the National Science Foundation awarded a grant for the development of a synthetic peptide, ACT1, aimed at treating AMD. This research focuses on the ocular delivery of ACT1, highlighting the interest in peptide-based therapies for this condition.
NSF - NATIONAL SCIENCE FOUNDATION

These studies underscore the active pursuit of peptide-based treatments for dry AMD within the U.S. research community.

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Yes , you are correct, there are US studies. Animal studies. However, I found a small human study 2013 in Retina Today but it was for peptides and wet AMD.

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@sjs1

investigated the use of a Fas-blocking peptide administered via eye drops. This research demonstrated that the peptide could reach the retina and mitigate degeneration by modulating inflammatory cytokines and inhibiting Fas-mediated apoptosis in animal models. The findings suggest potential therapeutic applications for dry AMD, though further studies are needed to assess its efficacy in humans.
PUBMED

Additionally, the National Science Foundation awarded a grant for the development of a synthetic peptide, ACT1, aimed at treating AMD. This research focuses on the ocular delivery of ACT1, highlighting the interest in peptide-based therapies for this condition.
NSF - NATIONAL SCIENCE FOUNDATION

These studies underscore the active pursuit of peptide-based treatments for dry AMD within the U.S. research community.

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Peptide-based therapies for AMD are in the experimental stages, with several showing potential in preclinical and early clinical trials. However, more extensive research and clinical validation are necessary to confirm their safety and efficacy. It's advisable to consult with your healthcare providers before considering new treatments, as they can offer guidance based on the most current and comprehensive information.

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@sjs1

Yes , you are correct, there are US studies. Animal studies. However, I found a small human study 2013 in Retina Today but it was for peptides and wet AMD.

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At least there's a start.
Most studies begin in animals.
Thank you for your information. Any glimmer of hope is great. Especially for someone who isn't that far along.

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@sjs1

Peptide-based therapies for AMD are in the experimental stages, with several showing potential in preclinical and early clinical trials. However, more extensive research and clinical validation are necessary to confirm their safety and efficacy. It's advisable to consult with your healthcare providers before considering new treatments, as they can offer guidance based on the most current and comprehensive information.

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Thank you for this information.
I would never try a treatment without consulting my specialist.
I want to keep my vision lol.

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