1. < Bones, Joints & Muscles

cymbalta for pain

Posted by srwolfe @srwolfe, Sep 19, 2023

I was prescribed cymbalta to help with overall body pain. After a week i was walking my dog and realized my pain was way down to almost to a livable pain. But the sweating was non stop. Especially at night i soaked my pillow and bed. My Dr had me stop cymbalta and my pain came roaring back. Anyone that can help me with this please let me know

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fcd99 | @fcd99 | 5 days ago
In reply to @pmci "Just a warning about cymbalta. I’m on a very low dose (30g every second day), having..." + (show)
@pmci

Just a warning about cymbalta. I’m on a very low dose (30g every second day), having started taking it about 10 years ago. Last year I tried to go off it, very gradually as advised, but a couple of weeks after completely stopping I had terrible and frightening withdrawal symptoms. I assume I’d been on cymbalta for too long.

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I was just prescribed 30 mg (daily) duloxetine for neuropathy pain, anxiety, and depression and 50 mg Trazodone for insomnia. I really want this combination to work, but am concerned about side effects. What has been your experience taking duloxetine at the lowest effective dose (e.g. 30 mg daily or 30 mg every other day)? Also did you experience bothersome side effects at this dose? Thanks in advance for replying.

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1 reply
derfly | @derfly | 5 days ago

Trazadone can hang around in the body long enough so you may feel "tired" the next morning (I've been on it yrs ago and I'm a RPh). You may not feel this it depends on body wt+ body fat.You usually overcome this after several days of Rx. Watch stomach side effects on other,, AND IF IT DOESN'T WORK FOR PAIN COMPLAIN ,YES COMPLAIN TO YOUR DR TO COVER IT BETTER ! Tx Rick

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derfly | @derfly | 5 days ago
In reply to @srwolfe "Ok I just came from my Dr and he wants me to try 20mg Cymbalta every..." + (show)
@srwolfe

Ok I just came from my Dr and he wants me to try 20mg Cymbalta every other day. Hopefully the extreme sweating will be les and manageable. I was originally using 30 mg Cymbalta a day. I was taking it at night. I'm going to try taking the 20 mg in the morning and see if the night sweats are less. I really hope this works. Back is killing me along with all the other constant pain of arthritis and multiple surgeries on hips, knees and shoulder. Please let me know if you have this same issue. The Cymbalta 30 mg was best pain medication I ever had prescribed but side effects were extreme

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DO NOT BE AFRAID TO USE LOW DOSE OPOIDS. THEY DON'T TURN YOU INTO A HAIRY DOPE FIEND. They block the pain ! I had to go on them for PSA and I'm a former Pharmacy DIRECTOR at NIDA National Institute of DRUG Abuse. If you have no history of Chemical Abuse in your family Hx than you should be fine. Tx Rick

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Pippa | @pmci | 4 days ago
In reply to @fcd99 "I was just prescribed 30 mg (daily) duloxetine for neuropathy pain, anxiety, and depression and 50..." + (show)
@fcd99

I was just prescribed 30 mg (daily) duloxetine for neuropathy pain, anxiety, and depression and 50 mg Trazodone for insomnia. I really want this combination to work, but am concerned about side effects. What has been your experience taking duloxetine at the lowest effective dose (e.g. 30 mg daily or 30 mg every other day)? Also did you experience bothersome side effects at this dose? Thanks in advance for replying.

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I had no negative side effects of taking 30mg duloxetine daily, except perhaps a negative effect on libido. Otherwise it was very effective. The negative effects of it for me were when I tried to come off this drug. That was terrifying. As I’ve said, I was on it for years before that. I strongly advise getting off it as soon as your doctor recommends you do so.

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cindisue | @cindisue | 4 days ago
In reply to @derfly "DO NOT BE AFRAID TO USE LOW DOSE OPOIDS. THEY DON'T TURN YOU INTO A HAIRY..." + (show)
@derfly

DO NOT BE AFRAID TO USE LOW DOSE OPOIDS. THEY DON'T TURN YOU INTO A HAIRY DOPE FIEND. They block the pain ! I had to go on them for PSA and I'm a former Pharmacy DIRECTOR at NIDA National Institute of DRUG Abuse. If you have no history of Chemical Abuse in your family Hx than you should be fine. Tx Rick

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derfly, what opioid med are you referring to? I don't believe Duloxetine is an opiod... Tramadol worked pretty good for my post hip surgery pain.

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cindisue | @cindisue | 4 days ago
In reply to @aus12 "I’m on 60 mg of Cymbalta for several months and still no relief from back pain...." + (show)
@aus12

I’m on 60 mg of Cymbalta for several months and still no relief from back pain. Interested to see what dose other people are on that relieved their pain

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aus12, you've taken it 6 months with no relief?? I'm wondering why you haven't gone back to your doctor and told them it's not working and demand something else! I went thru this....for anxiety and sleep issues. If a med the doctor prescribed didn't work or gave me side effects I couldn't put up with, I was back at the doctors office, asking to try something else! You don't give up until you get the right medication for your issues! Good luck! ❤️

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cindisue | @cindisue | 4 days ago
In reply to @celia16 "I’m very dismayed to read about constipation. I already have that. But I need something for..." + (show)
@celia16

I’m very dismayed to read about constipation. I already have that. But I need something for the pain from my B12 deficiency. Burning is intense…intermittent. I can’t tolerate Gabapentin. I guess I’ll have to resume taking Miralax. And, give. Cymbalta a chance.

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celia16, why aren't you taking a B-12 supplement?

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cindisue | @cindisue | 4 days ago
In reply to @larak "Cymbalta does help with pain. But, for me, it made depression worse. And I experienced truly..." + (show)
@larak

Cymbalta does help with pain.

But, for me, it made depression worse. And I experienced truly evil withdrawal symptoms while tapering it down: insomnia, hand tremors, panic attacks, etc.

Gabapentin is another that had wicked withdrawal symptoms for me. Panic attacks even worse than the ones Gabapentin was causing in the first place.

I was on both for anxiety & depression for 4 years. I liked not having as much joint pain as a side effect. But they were clearly NOT helping for the anxiety & depression.

It took months to taper and get through the withdrawal symptoms. But I like having my brain back.

Ibuprofen at the level I'm taking likely isn't good. But I am enjoying not having anxiety attacks & major depression.

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Lara K, just wanted to suggest to you the medication Amitriptyline....it helps depression, anxiety, sleep issues and some pain issues. I did not know ibuprofen was good for depression and anxiety.

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celia16 | @celia16 | 4 days ago
In reply to @cindisue "celia16, why aren't you taking a B-12 supplement?" + (show)
@cindisue

celia16, why aren't you taking a B-12 supplement?

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I do take a B12 supplement. Thank you for asking. Maybe that wasn’t clear in my previous post.

Since June, I’ve had more improvement. I’ve been on the B12 supplement for a while and I no longer have burning like I did in June. I’m very grateful for that and that the paresthesia in my feet is mostly gone. Hopefully it will completely resolve. So, I no longer need Gabapentin. I do still get occasional awakening in the night to my hands feeling asleep. Taking that up with my neurologist at the next visit. Constipation improved too.

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Lara K | @larak | 4 days ago
In reply to @cindisue "Lara K, just wanted to suggest to you the medication Amitriptyline....it helps depression, anxiety, sleep issues..." + (show)
@cindisue

Lara K, just wanted to suggest to you the medication Amitriptyline....it helps depression, anxiety, sleep issues and some pain issues. I did not know ibuprofen was good for depression and anxiety.

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Thank you. I have thought about non-SSRI meds. There is a new one - Auvelity? - that my psychiatrist wants to try.

Ibuprofen is only good for depression and anxiety in the sense that not being in pain constantly is a good thing.

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